Obesity is an energy-rich condition associated with overnutrition, which impairs systemic metabolic homeostasis and elicits stress. It also activates an inflammatory process in metabolically active sites, such as white adipose tissue, liver, and immune cells. As consequence, increased circulating levels of proinflammatory cytokines, hormone-like molecules, and other inflammatory markers are induced. This determines a chronic active inflammatory condition, associated with the development of the obesityrelated inflammatory diseases. This paper describes the role of adipose tissue and the biological effects of many adipokines in these diseases.

Balistreri, C.R., Caruso, C., Candore, G. (2010). The Role of Adipose Tissue and Adipokines in Obesity-Related Inflammatory Diseases. MEDIATORS OF INFLAMMATION, Article ID 802078(80) [doi:10.1155/2010/802078].

The Role of Adipose Tissue and Adipokines in Obesity-Related Inflammatory Diseases

BALISTRERI, Carmela Rita;CARUSO, Calogero;CANDORE, Giuseppina
2010-01-01

Abstract

Obesity is an energy-rich condition associated with overnutrition, which impairs systemic metabolic homeostasis and elicits stress. It also activates an inflammatory process in metabolically active sites, such as white adipose tissue, liver, and immune cells. As consequence, increased circulating levels of proinflammatory cytokines, hormone-like molecules, and other inflammatory markers are induced. This determines a chronic active inflammatory condition, associated with the development of the obesityrelated inflammatory diseases. This paper describes the role of adipose tissue and the biological effects of many adipokines in these diseases.
2010
Settore MED/04 - Patologia Generale
Balistreri, C.R., Caruso, C., Candore, G. (2010). The Role of Adipose Tissue and Adipokines in Obesity-Related Inflammatory Diseases. MEDIATORS OF INFLAMMATION, Article ID 802078(80) [doi:10.1155/2010/802078].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/59326
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