Primary retroperitoneal sarcomas (RPS) represent around 10–16% of all sarcomas, with liposarcomas and leiomyosarcomas being the most common subtypes. RPS have some peculiar characteristics, imaging appearances, worse prognosis, and complications compared to other locations of sarcoma. Commonly, RPS primarily present as large masses, progressively encasing adjacent structures, causing mass effect, and complications. RPS diagnosis is often challenging, and these tumors may be overlooked; however, failure to recognize RPS characteristics leads to a worse prognosis for the patients. Surgery is the only recognized curative treatment, but the anatomical constraints of the retroperitoneum limit the ability to achieve wide resection margins; therefore, these tumors have a high rate of recurrence, and require long-term follow-up. The radiologist has an important role in the diagnosis of RPS, the definition of their extent, and their follow-up. Specific knowledge of the main imaging findings is required to reach an early diagnosis, and, ultimately, to guarantee the best patient management. This article provides an overview of the current knowledge regarding cross-sectional imaging features of patients with retroperitoneal sarcomas, presenting tips and tricks to improve imaging diagnosis of RPS.

Porrello, G., Cannella, R., Randazzo, A., Badalamenti, G., Brancatelli, G., Vernuccio, F. (2023). CT and MR Imaging of Retroperitoneal Sarcomas: A Practical Guide for the Radiologist [10.3390/cancers15112985].

CT and MR Imaging of Retroperitoneal Sarcomas: A Practical Guide for the Radiologist

Porrello, Giorgia
Primo
Writing – Original Draft Preparation
;
Cannella, Roberto
Secondo
Writing – Review & Editing
;
Randazzo, Angelo
Writing – Original Draft Preparation
;
Badalamenti, Giuseppe
Data Curation
;
Brancatelli, Giuseppe
Penultimo
Supervision
;
Vernuccio, Federica
Ultimo
Writing – Review & Editing
2023-05-30

Abstract

Primary retroperitoneal sarcomas (RPS) represent around 10–16% of all sarcomas, with liposarcomas and leiomyosarcomas being the most common subtypes. RPS have some peculiar characteristics, imaging appearances, worse prognosis, and complications compared to other locations of sarcoma. Commonly, RPS primarily present as large masses, progressively encasing adjacent structures, causing mass effect, and complications. RPS diagnosis is often challenging, and these tumors may be overlooked; however, failure to recognize RPS characteristics leads to a worse prognosis for the patients. Surgery is the only recognized curative treatment, but the anatomical constraints of the retroperitoneum limit the ability to achieve wide resection margins; therefore, these tumors have a high rate of recurrence, and require long-term follow-up. The radiologist has an important role in the diagnosis of RPS, the definition of their extent, and their follow-up. Specific knowledge of the main imaging findings is required to reach an early diagnosis, and, ultimately, to guarantee the best patient management. This article provides an overview of the current knowledge regarding cross-sectional imaging features of patients with retroperitoneal sarcomas, presenting tips and tricks to improve imaging diagnosis of RPS.
30-mag-2023
Settore MED/36 - Diagnostica Per Immagini E Radioterapia
Porrello, G., Cannella, R., Randazzo, A., Badalamenti, G., Brancatelli, G., Vernuccio, F. (2023). CT and MR Imaging of Retroperitoneal Sarcomas: A Practical Guide for the Radiologist [10.3390/cancers15112985].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/592604
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