Calcium phosphate/chitosan/collagen composite coating on AISI 304 stainless steel was investigated. Coatings were realized by galvanic coupling that occurs without an external power supply because it begins with the coupling between two metals with different standard electrochemical potentials. The process consists of the co-deposition of the three components with the calcium phosphate crystals incorporated into the polymeric composite of chitosan and collagen. Physical-chemical characterizations of the samples were executed to evaluate morphology and chemical composition. Morphological analyses have shown that the surface of the stainless steel is covered by the deposit, which has a very rough surface. XRD, Raman, and FTIR characterizations highlighted the presence of both calcium phosphate compounds and polymers. The coatings undergo a profound variation after aging in simulated body fluid, both in terms of composition and structure. The tests, carried out in simulated body fluid to scrutinize the corrosion resistance, have shown the protective behavior of the coating. In particular, the corrosion potential moved toward higher values with respect to uncoated steel, while the corrosion current density decreased. This good behavior was further confirmed by the very low quantification of the metal ions (practically absent) released in simulated body fluid during aging. Cytotoxicity tests using a pre-osteoblasts MC3T3-E1 cell line were also performed that attest the biocompatibility of the coating.

Zanca, C., Patella, B., Capuana, E., Lopresti, F., Brucato, V., Carfì Pavia, F., et al. (2022). Behavior of Calcium Phosphate-Chitosan-Collagen Composite Coating on AISI 304 for Orthopedic Applications. POLYMERS, 14(23) [10.3390/polym14235108].

Behavior of Calcium Phosphate-Chitosan-Collagen Composite Coating on AISI 304 for Orthopedic Applications

Zanca, Claudio
Membro del Collaboration Group
;
Patella, Bernardo
Membro del Collaboration Group
;
Capuana, Elisa
Membro del Collaboration Group
;
Lopresti, Francesco
Membro del Collaboration Group
;
Brucato, Valerio
Membro del Collaboration Group
;
Carfì Pavia, Francesco
Membro del Collaboration Group
;
La Carrubba, Vincenzo
Membro del Collaboration Group
;
Inguanta, Rosalinda
Membro del Collaboration Group
2022-11-24

Abstract

Calcium phosphate/chitosan/collagen composite coating on AISI 304 stainless steel was investigated. Coatings were realized by galvanic coupling that occurs without an external power supply because it begins with the coupling between two metals with different standard electrochemical potentials. The process consists of the co-deposition of the three components with the calcium phosphate crystals incorporated into the polymeric composite of chitosan and collagen. Physical-chemical characterizations of the samples were executed to evaluate morphology and chemical composition. Morphological analyses have shown that the surface of the stainless steel is covered by the deposit, which has a very rough surface. XRD, Raman, and FTIR characterizations highlighted the presence of both calcium phosphate compounds and polymers. The coatings undergo a profound variation after aging in simulated body fluid, both in terms of composition and structure. The tests, carried out in simulated body fluid to scrutinize the corrosion resistance, have shown the protective behavior of the coating. In particular, the corrosion potential moved toward higher values with respect to uncoated steel, while the corrosion current density decreased. This good behavior was further confirmed by the very low quantification of the metal ions (practically absent) released in simulated body fluid during aging. Cytotoxicity tests using a pre-osteoblasts MC3T3-E1 cell line were also performed that attest the biocompatibility of the coating.
Settore ING-IND/23 - Chimica Fisica Applicata
Settore ING-IND/34 - Bioingegneria Industriale
Settore ING-IND/22 - Scienza E Tecnologia Dei Materiali
https://www.mdpi.com/2073-4360/14/23/5108
Zanca, C., Patella, B., Capuana, E., Lopresti, F., Brucato, V., Carfì Pavia, F., et al. (2022). Behavior of Calcium Phosphate-Chitosan-Collagen Composite Coating on AISI 304 for Orthopedic Applications. POLYMERS, 14(23) [10.3390/polym14235108].
File in questo prodotto:
File Dimensione Formato  
polymers-14-05108.pdf

accesso aperto

Tipologia: Versione Editoriale
Dimensione 6.07 MB
Formato Adobe PDF
6.07 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/576988
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 0
  • ???jsp.display-item.citation.isi??? ND
social impact