The ability to track drugs inside of cells and tumours has been highly valuable in cancer research and diagnosis. Metal complexes add attractive features to fluorescent drugs, such as targeting and specificity, solubility and uptake or photophysical properties. This review focuses on the latest fluorescent metal-based complexes, their cellular targets, photophysical properties and possible anticancer effects.
de Almeida A., Bonsignore R. (2020). Fluorescent metal-based complexes as cancer probes. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 30(13) [10.1016/j.bmcl.2020.127219].
Fluorescent metal-based complexes as cancer probes
Bonsignore R.
2020-01-01
Abstract
The ability to track drugs inside of cells and tumours has been highly valuable in cancer research and diagnosis. Metal complexes add attractive features to fluorescent drugs, such as targeting and specificity, solubility and uptake or photophysical properties. This review focuses on the latest fluorescent metal-based complexes, their cellular targets, photophysical properties and possible anticancer effects.
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