Population ageing is a great achievement of humanity, but it also represents a challenge that the Western world is currently facing, as ageing is associated with increased susceptibility to age-related inflammatory diseases. Therefore, it is necessary to fully understand the mechanisms of healthy ageing to prevent the harmful aspects of ageing. The study of long living individuals (LLIs) is a great model for trying to achieve this goal. Accordingly, the oxy-inflammatory status of Sicilian LLIs was reviewed in the present paper. Based on the reported data, anti-inflammatory and anti-oxidative stress strategies have been discussed, useful for delaying or avoiding the onset of age-related diseases, thus favouring a healthy ageing process.

Caruso, C., Accardi, G., Aiello, A., Calabrò, A., Ligotti, M.E., Candore, G. (2022). Lessons from Sicilian Centenarians for Anti-Ageing Medicine. The Oxi-Inflammatory Status [10.37825/2239-9754.1036].

Lessons from Sicilian Centenarians for Anti-Ageing Medicine. The Oxi-Inflammatory Status

Caruso, Calogero
;
Accardi, Giulia;Aiello, Anna;Calabrò, Anna;Ligotti, Mattia E;Candore, Giuseppina
2022-09-01

Abstract

Population ageing is a great achievement of humanity, but it also represents a challenge that the Western world is currently facing, as ageing is associated with increased susceptibility to age-related inflammatory diseases. Therefore, it is necessary to fully understand the mechanisms of healthy ageing to prevent the harmful aspects of ageing. The study of long living individuals (LLIs) is a great model for trying to achieve this goal. Accordingly, the oxy-inflammatory status of Sicilian LLIs was reviewed in the present paper. Based on the reported data, anti-inflammatory and anti-oxidative stress strategies have been discussed, useful for delaying or avoiding the onset of age-related diseases, thus favouring a healthy ageing process.
Settore MED/04 - Patologia Generale
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673988/
Caruso, C., Accardi, G., Aiello, A., Calabrò, A., Ligotti, M.E., Candore, G. (2022). Lessons from Sicilian Centenarians for Anti-Ageing Medicine. The Oxi-Inflammatory Status [10.37825/2239-9754.1036].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/575300
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