Prostate cancer (PCa) represents the fourth most common cancer and the fifth leading cause of cancer death of men worldwide. Multiparametric MRI (mp-MRI) has high sensitivity and specificity in the detection of PCa, and it is currently the most widely used imaging technique for tumor localization and cancer staging. mp-MRI plays a key role in risk stratification of naive patients, in active surveillance for low-risk patients, and in monitoring recurrence after definitive therapy. Radiomics is an emerging and promising tool which allows a quantitative tumor evaluation from radiological images via conversion of digital images into mineable high-dimensional data. The purpose of radiomics is to increase the features available to detect PCa, to avoid unnecessary biopsies, to define tumor aggressiveness, and to monitor post-treatment recurrence of PCa. The integration of radiomics data, including different imaging modalities (such as PET-CT) and other clinical and histopathological data, could improve the prediction of tumor aggressiveness as well as guide clinical decisions and patient management. The purpose of this review is to describe the current research applications of radiomics in PCa on MR images.

Midiri, F., Vernuccio, F., Purpura, P., Alongi, P., Bartolotta, T.V. (2021). Multiparametric MRI and Radiomics in Prostate Cancer: A Review of the Current Literature [10.3390/diagnostics11101829].

Multiparametric MRI and Radiomics in Prostate Cancer: A Review of the Current Literature

Midiri, Federico
;
Vernuccio, Federica;Purpura, Pierpaolo;Bartolotta, Tommaso Vincenzo
2021-10-03

Abstract

Prostate cancer (PCa) represents the fourth most common cancer and the fifth leading cause of cancer death of men worldwide. Multiparametric MRI (mp-MRI) has high sensitivity and specificity in the detection of PCa, and it is currently the most widely used imaging technique for tumor localization and cancer staging. mp-MRI plays a key role in risk stratification of naive patients, in active surveillance for low-risk patients, and in monitoring recurrence after definitive therapy. Radiomics is an emerging and promising tool which allows a quantitative tumor evaluation from radiological images via conversion of digital images into mineable high-dimensional data. The purpose of radiomics is to increase the features available to detect PCa, to avoid unnecessary biopsies, to define tumor aggressiveness, and to monitor post-treatment recurrence of PCa. The integration of radiomics data, including different imaging modalities (such as PET-CT) and other clinical and histopathological data, could improve the prediction of tumor aggressiveness as well as guide clinical decisions and patient management. The purpose of this review is to describe the current research applications of radiomics in PCa on MR images.
3-ott-2021
Settore MED/36 - Diagnostica Per Immagini E Radioterapia
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534893/
Midiri, F., Vernuccio, F., Purpura, P., Alongi, P., Bartolotta, T.V. (2021). Multiparametric MRI and Radiomics in Prostate Cancer: A Review of the Current Literature [10.3390/diagnostics11101829].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/573266
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