Objective: To develop a dedicated Italian chronic migraine (CM) database (IRON project) to overcome disease misconceptions, improve clinical administration, reduce patients' burden, and rationalize economic resource allotment.Background: Proper CM management requires a comprehensive appraisal of its full clinical, social, and economic complexity.Methods: In this cross-sectional study, CM patients were screened in 24 certified headache centers with face-to-face interviews. Information on sociodemographic factors, medical history, characteristics of CM, and of prior episodic migraine (EM), and healthcare resource use was gathered using a semistructured web-based questionnaire.Results: A total of 866 CM patients were enrolled. CM started similar to 20 years after EM onset (age at EM onset 17.4 +/- 9.1 vs. age at CM onset 35.3 +/- 12.5 [mean +/- SD]). CM prophylaxis, used by 430/866 (49.6%) of the patients, was often ineffective, not tolerated, and prematurely discontinued. Medications and diagnostic workup, frequently inappropriate, were mostly subsidized by the Italian national health service. CM patients with >= 25 headache days/month revealed substantial clinical differences and heavier disability and economic burden compared with those with <25 headache days/month.Conclusions: CM is a heterogeneous headache disorder deserving more in-depth clinical characterization, sharper diagnostic criteria, and tailored treatments. CM registries are expected to improve clinical management, resulting in increased disease awareness, better healthcare resource allocation, and reduced economic burden.

Barbanti, P., Fofi, L., Grazzi, L., Vernieri, F., Camarda, C., Torelli, P., et al. (2021). Clinical features, disease progression and use of healthcare resources in a large sample of 866 patients from 24 headache centers: A real-life perspective from the Italian chROnic migraiNe (IRON) project. HEADACHE, 61(6), 936-950 [10.1111/head.14123].

Clinical features, disease progression and use of healthcare resources in a large sample of 866 patients from 24 headache centers: A real-life perspective from the Italian chROnic migraiNe (IRON) project

Camarda, Cecilia
Membro del Collaboration Group
;
2021-06

Abstract

Objective: To develop a dedicated Italian chronic migraine (CM) database (IRON project) to overcome disease misconceptions, improve clinical administration, reduce patients' burden, and rationalize economic resource allotment.Background: Proper CM management requires a comprehensive appraisal of its full clinical, social, and economic complexity.Methods: In this cross-sectional study, CM patients were screened in 24 certified headache centers with face-to-face interviews. Information on sociodemographic factors, medical history, characteristics of CM, and of prior episodic migraine (EM), and healthcare resource use was gathered using a semistructured web-based questionnaire.Results: A total of 866 CM patients were enrolled. CM started similar to 20 years after EM onset (age at EM onset 17.4 +/- 9.1 vs. age at CM onset 35.3 +/- 12.5 [mean +/- SD]). CM prophylaxis, used by 430/866 (49.6%) of the patients, was often ineffective, not tolerated, and prematurely discontinued. Medications and diagnostic workup, frequently inappropriate, were mostly subsidized by the Italian national health service. CM patients with >= 25 headache days/month revealed substantial clinical differences and heavier disability and economic burden compared with those with <25 headache days/month.Conclusions: CM is a heterogeneous headache disorder deserving more in-depth clinical characterization, sharper diagnostic criteria, and tailored treatments. CM registries are expected to improve clinical management, resulting in increased disease awareness, better healthcare resource allocation, and reduced economic burden.
Settore MED/26 - Neurologia
https://headachejournal.onlinelibrary.wiley.com/doi/10.1111/head.14123
Barbanti, P., Fofi, L., Grazzi, L., Vernieri, F., Camarda, C., Torelli, P., et al. (2021). Clinical features, disease progression and use of healthcare resources in a large sample of 866 patients from 24 headache centers: A real-life perspective from the Italian chROnic migraiNe (IRON) project. HEADACHE, 61(6), 936-950 [10.1111/head.14123].
File in questo prodotto:
File Dimensione Formato  
Headache - 2021 - Barbanti - Clinical features disease progression and use of healthcare resources in a large sample of.pdf

non disponibili

Tipologia: Versione Editoriale
Dimensione 509.68 kB
Formato Adobe PDF
509.68 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/566102
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 3
  • ???jsp.display-item.citation.isi??? 3
social impact