A number of small cross sectional studies have demonstrated that hypovitaminosis D (represented by low 25 hydroxyvitamin D (25OHD) levels) is associated with orthostatic hypotension (OH). We investigated if hypovitaminosis D is associated with the onset of OH in older adults over a follow-up of 4.4 years. 25OHD was categorized using sex-specific quartiles; OH was defined as a drop of ≤20 mm Hg in systolic or ≤10 mm Hg in diastolic blood pressure <3 minutes of standing. Among 1308 elderly without OH at baseline, using an adjusted logistic regression analysis and taking those with higher baseline serum 25OHD as reference, there was a significant increase in the onset of OH in those with lower serum 25OHD levels. The association was significant only in women when we stratified by sex. In conclusion, hypovitaminosis D predicts the onset of OH in older adults, particularly in women. © 2016 American Society of Hypertension

Veronese, N., Trevisan, C., Bolzetta, F., De Rui, M., Zambon, S., Musacchio, E., et al. (2016). Hypovitaminosis D predicts the onset of orthostatic hypotension in older adults. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION, 10(9), 724-732 [10.1016/j.jash.2016.06.038].

Hypovitaminosis D predicts the onset of orthostatic hypotension in older adults

Veronese, N.;
2016

Abstract

A number of small cross sectional studies have demonstrated that hypovitaminosis D (represented by low 25 hydroxyvitamin D (25OHD) levels) is associated with orthostatic hypotension (OH). We investigated if hypovitaminosis D is associated with the onset of OH in older adults over a follow-up of 4.4 years. 25OHD was categorized using sex-specific quartiles; OH was defined as a drop of ≤20 mm Hg in systolic or ≤10 mm Hg in diastolic blood pressure <3 minutes of standing. Among 1308 elderly without OH at baseline, using an adjusted logistic regression analysis and taking those with higher baseline serum 25OHD as reference, there was a significant increase in the onset of OH in those with lower serum 25OHD levels. The association was significant only in women when we stratified by sex. In conclusion, hypovitaminosis D predicts the onset of OH in older adults, particularly in women. © 2016 American Society of Hypertension
Veronese, N., Trevisan, C., Bolzetta, F., De Rui, M., Zambon, S., Musacchio, E., et al. (2016). Hypovitaminosis D predicts the onset of orthostatic hypotension in older adults. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION, 10(9), 724-732 [10.1016/j.jash.2016.06.038].
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/565931
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