Objective: Head and neck involvement in Kaposi’s Sarcoma (KS) is not unusual . However, laryngeal involvement is a relatively infrequent manifestation and ENT specialists should consider it in differential diagnosis in laryngeal lesions of AIDS patients and/or subjects from the Mediterranean area. Methods: Case report and review of the literature in English Clinical Case: Male patient presenting with a three- month history of cough and acute dispnoea. Laryngoscopy identified a laryngeal mass occluding the glottic plane. Tracheotomy was then performed and the laryngeal lesion was removed. Histopathology showed neoplastic spindle cells that were positive to immunostain with CD-31 and CD-34, and immunoreactivity for HHV-8 was present. A diagnosis of KS was then suspected and confirmed after dermatological inspection. Conclusions: Purple vascular mass lesions should lead in ENT to a high index of suspicion to exclude systemic diseases. Laryngeal KS must be included in the differential diagnosis of pigmented laryngeal lesions to plan correct management

Dispenza, F., Ballacchino, A., Di Bernardo, A., Mathur, N., Gallina, S. (2010). Localisation of mediterranean Kaposi's sarcoma in Morgagni's ventricle. B-ENT, 6(4), 289-293.

Localisation of mediterranean Kaposi's sarcoma in Morgagni's ventricle

DISPENZA, Francesco;DI BERNARDO, Andrea;GALLINA, Salvatore
2010-01-01

Abstract

Objective: Head and neck involvement in Kaposi’s Sarcoma (KS) is not unusual . However, laryngeal involvement is a relatively infrequent manifestation and ENT specialists should consider it in differential diagnosis in laryngeal lesions of AIDS patients and/or subjects from the Mediterranean area. Methods: Case report and review of the literature in English Clinical Case: Male patient presenting with a three- month history of cough and acute dispnoea. Laryngoscopy identified a laryngeal mass occluding the glottic plane. Tracheotomy was then performed and the laryngeal lesion was removed. Histopathology showed neoplastic spindle cells that were positive to immunostain with CD-31 and CD-34, and immunoreactivity for HHV-8 was present. A diagnosis of KS was then suspected and confirmed after dermatological inspection. Conclusions: Purple vascular mass lesions should lead in ENT to a high index of suspicion to exclude systemic diseases. Laryngeal KS must be included in the differential diagnosis of pigmented laryngeal lesions to plan correct management
Settore MED/06 - Oncologia Medica
Settore MED/31 - Otorinolaringoiatria
Dispenza, F., Ballacchino, A., Di Bernardo, A., Mathur, N., Gallina, S. (2010). Localisation of mediterranean Kaposi's sarcoma in Morgagni's ventricle. B-ENT, 6(4), 289-293.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/55714
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