Catalase gene (CAT) polymorphisms were analyzed as responsible for the deficiency of catalase enzyme activity and concomitant accumulation of excessive hydrogen peroxide in Vitiligo patients. Catalase is a well known oxidative stress regulator that could play an important role in the pathogenesis of Vitiligo. This study was conducted to evaluate three CAT gene polymorphisms (-89A/T, 389C/T, 419C/T) and their association with Vitiligo susceptibility in Sicilian population.

Caputo, V., Niceta, M., Fiorella, S., La Vecchia, M., Bastonini, E., Bongiorno, M.R., et al. (2018). Vitiligo susceptibility and catalase gene (CAT) polymorphisms in sicilian population. GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA, 153(5), 619-623 [10.23736/S0392-0488.17.05488-8].

Vitiligo susceptibility and catalase gene (CAT) polymorphisms in sicilian population

Caputo, Valentina;Niceta, Marcello;Fiorella, Santi;LA VECCHIA, Marco;Bongiorno, Maria R;Pistone, Giuseppe
2018

Abstract

Catalase gene (CAT) polymorphisms were analyzed as responsible for the deficiency of catalase enzyme activity and concomitant accumulation of excessive hydrogen peroxide in Vitiligo patients. Catalase is a well known oxidative stress regulator that could play an important role in the pathogenesis of Vitiligo. This study was conducted to evaluate three CAT gene polymorphisms (-89A/T, 389C/T, 419C/T) and their association with Vitiligo susceptibility in Sicilian population.
Caputo, V., Niceta, M., Fiorella, S., La Vecchia, M., Bastonini, E., Bongiorno, M.R., et al. (2018). Vitiligo susceptibility and catalase gene (CAT) polymorphisms in sicilian population. GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA, 153(5), 619-623 [10.23736/S0392-0488.17.05488-8].
File in questo prodotto:
File Dimensione Formato  
lavoro VITILIGO.pdf

non disponibili

Tipologia: Versione Editoriale
Dimensione 3.2 MB
Formato Adobe PDF
3.2 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/514735
Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus ND
  • ???jsp.display-item.citation.isi??? 2
social impact