Cornelian cherry fruit extract rich in anthocyanins and iridoids was encapsulated in the halloysite nanotubes in order to obtain a stable nanoscale system for better delivery and prolonged release of bioactive constituents. The cyclic vacuum technique was used for halloysite nanotubes-cornelian cherry composite preparation and the loading of 8.5 wt% was achieved. Pure cornelian cherry extract exhibited antiproliferative effect on HT-29, MCF7, and MRC-5 cells, pristine halloysite nanotubes affected the growth of MCF7 cells, while halloysite nanotubes-cornelian cherry composites demonstrated proliferative activity in all tested cells. The sustained release of anthocyanins was achieved by this encapsulation strategy. Additional implementation of halloysite nanotubes-cornelian cherry into yogurt prolonged the release of iridoid molecules. Obtained results indicate that halloysite nanoclay is a suitable nanocarrier for cornelian cherry constituents that can be utilized in food and pharmaceutical industries.

Blagojevic B., Cetojevic-Simin D., Parisi F., Lazzara G., & Popovic B.M. (2020). Halloysite nanotubes as a carrier of cornelian cherry (Cornus mas L.) bioactives. LEBENSMITTEL-WISSENSCHAFT + TECHNOLOGIE, 134 [10.1016/j.lwt.2020.110247].

Halloysite nanotubes as a carrier of cornelian cherry (Cornus mas L.) bioactives

Parisi F.;Lazzara G.;
2020

Abstract

Cornelian cherry fruit extract rich in anthocyanins and iridoids was encapsulated in the halloysite nanotubes in order to obtain a stable nanoscale system for better delivery and prolonged release of bioactive constituents. The cyclic vacuum technique was used for halloysite nanotubes-cornelian cherry composite preparation and the loading of 8.5 wt% was achieved. Pure cornelian cherry extract exhibited antiproliferative effect on HT-29, MCF7, and MRC-5 cells, pristine halloysite nanotubes affected the growth of MCF7 cells, while halloysite nanotubes-cornelian cherry composites demonstrated proliferative activity in all tested cells. The sustained release of anthocyanins was achieved by this encapsulation strategy. Additional implementation of halloysite nanotubes-cornelian cherry into yogurt prolonged the release of iridoid molecules. Obtained results indicate that halloysite nanoclay is a suitable nanocarrier for cornelian cherry constituents that can be utilized in food and pharmaceutical industries.
Blagojevic B., Cetojevic-Simin D., Parisi F., Lazzara G., & Popovic B.M. (2020). Halloysite nanotubes as a carrier of cornelian cherry (Cornus mas L.) bioactives. LEBENSMITTEL-WISSENSCHAFT + TECHNOLOGIE, 134 [10.1016/j.lwt.2020.110247].
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/492454
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