Background: Eosinophilic granuloma is the benign form of Langerhans cell histiocytosis, a rare proliferative disorder. Skull osteolytic lesions are quite frequently encountered. Case report: We report the case of a 16 year old boy who was admitted to our Department with a painful swelling left frontal mass. A diagnosis of eosinophilic granuloma was presumed on the basis of the neuroradiological findings. Surgical removal of the lesion was achieved and the bone defect reconstructed by autologous fibrin glue and a titanium mesh. Histopathology confirmed the diagnosis. Conclusion: Although uncommon, eosinophilic granuloma should be considered in the differential diagnosis in case of an osteolytic calvarial lesion.

Imperato A., Iacopino D., Graziano F., Guli C., Giugno A., Basile L., et al. (2016). Eosinophilic granuloma of the skull vault: A case report. CURRENT PEDIATRIC RESEARCH, 20(1-2), 210-212.

Eosinophilic granuloma of the skull vault: A case report

Imperato A.;Iacopino D.
;
Giugno A.;
2016

Abstract

Background: Eosinophilic granuloma is the benign form of Langerhans cell histiocytosis, a rare proliferative disorder. Skull osteolytic lesions are quite frequently encountered. Case report: We report the case of a 16 year old boy who was admitted to our Department with a painful swelling left frontal mass. A diagnosis of eosinophilic granuloma was presumed on the basis of the neuroradiological findings. Surgical removal of the lesion was achieved and the bone defect reconstructed by autologous fibrin glue and a titanium mesh. Histopathology confirmed the diagnosis. Conclusion: Although uncommon, eosinophilic granuloma should be considered in the differential diagnosis in case of an osteolytic calvarial lesion.
Settore MED/27 - Neurochirurgia
Imperato A., Iacopino D., Graziano F., Guli C., Giugno A., Basile L., et al. (2016). Eosinophilic granuloma of the skull vault: A case report. CURRENT PEDIATRIC RESEARCH, 20(1-2), 210-212.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/485709
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