OBJECTIVES: To analyze psychological profiles, pain and oral symptoms in patients with oral lichen planus (OLP).MATERIALS AND METHODS: 300 patients with keratotic OLP (K-OLP; reticular, papular, plaque-like subtypes), 300 patients with predominant non-keratotic OLP (nK-OLP; erythematosus atrophic, erosive, ulcerative, bullous subtypes) and 300 controls were recruited in 15 universities. The number of oral sites involved and oral symptoms were recorded. The Numeric Rating Scale (NRS), Total Pain Rating Index (T-PRI), Hamilton Rating Scales for Depression and for Anxiety (HAM-D and HAM-A), Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS) were administered.RESULTS: The OLP patients, especially the nK-OLP, showed higher scores in the NRS, T-PRI, HAM-D, HAM-A and PSQI compared with the controls (p-value<.001** ). A positive correlation between the NRS, T-PRI, HAM-A, HAM-D and PSQI was found with the number of oral symptoms and number of oral sites involved. Pain was reported in 67.3 % of nK-OLP and 49.7% of K-OLP cases with poor correspondence between the site of lesions and the site of the symptoms.CONCLUSIONS: Mood disorders are frequently associated with OLP with an unexpected symptomatology correlated with the number of oral symptoms and with the extension of disease suggesting a peripheral neuropathy.

Adamo, D., Calabria, E., Coppola, N., Lo Muzio, L., Giuliani, M., Bizzoca, M.E., et al. (2021). Psychological profile and unexpected pain in oral lichen planus: a case-control multicenter SIPMO study. ORAL DISEASES [10.1111/odi.13787].

Psychological profile and unexpected pain in oral lichen planus: a case-control multicenter SIPMO study

Campisi, Giuseppina;Panzarella, Vera;
2021

Abstract

OBJECTIVES: To analyze psychological profiles, pain and oral symptoms in patients with oral lichen planus (OLP).MATERIALS AND METHODS: 300 patients with keratotic OLP (K-OLP; reticular, papular, plaque-like subtypes), 300 patients with predominant non-keratotic OLP (nK-OLP; erythematosus atrophic, erosive, ulcerative, bullous subtypes) and 300 controls were recruited in 15 universities. The number of oral sites involved and oral symptoms were recorded. The Numeric Rating Scale (NRS), Total Pain Rating Index (T-PRI), Hamilton Rating Scales for Depression and for Anxiety (HAM-D and HAM-A), Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS) were administered.RESULTS: The OLP patients, especially the nK-OLP, showed higher scores in the NRS, T-PRI, HAM-D, HAM-A and PSQI compared with the controls (p-value<.001** ). A positive correlation between the NRS, T-PRI, HAM-A, HAM-D and PSQI was found with the number of oral symptoms and number of oral sites involved. Pain was reported in 67.3 % of nK-OLP and 49.7% of K-OLP cases with poor correspondence between the site of lesions and the site of the symptoms.CONCLUSIONS: Mood disorders are frequently associated with OLP with an unexpected symptomatology correlated with the number of oral symptoms and with the extension of disease suggesting a peripheral neuropathy.
Adamo, D., Calabria, E., Coppola, N., Lo Muzio, L., Giuliani, M., Bizzoca, M.E., et al. (2021). Psychological profile and unexpected pain in oral lichen planus: a case-control multicenter SIPMO study. ORAL DISEASES [10.1111/odi.13787].
File in questo prodotto:
File Dimensione Formato  
odi13787.pdf_compressed1.pdf

accesso aperto

Descrizione: This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi:10.1111/odi.13787
Tipologia: Versione Editoriale
Dimensione 421.96 kB
Formato Adobe PDF
421.96 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/480546
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 5
  • ???jsp.display-item.citation.isi??? 6
social impact