Study question: The aim was to determine if HPVs affect spermatozoa DNA integrity. To resolve the discrepancy regarding the association between HPV infections and sperm DNA damage. Summary answer: To elucidate if HPV impairs DNA integrity, we suggest to investigate HPV DNA positivity in spermatozoa by a differential lysis procedure before TUNEL assay.
schillaci R, Notari T, Capra G, Ragusa MA, Roccheri MC, Perino A, et al. (2020). Sperm DNA integrity and human papillomavirus (HPV) infections: a controversy that could be resolved by a new molecular approach. HUMAN REPRODUCTION, 35(1).
Sperm DNA integrity and human papillomavirus (HPV) infections: a controversy that could be resolved by a new molecular approach
schillaci R;Capra G;Ragusa MA;Roccheri MC;Perino A;Bosco L
2020-01-01
Abstract
Study question: The aim was to determine if HPVs affect spermatozoa DNA integrity. To resolve the discrepancy regarding the association between HPV infections and sperm DNA damage. Summary answer: To elucidate if HPV impairs DNA integrity, we suggest to investigate HPV DNA positivity in spermatozoa by a differential lysis procedure before TUNEL assay.
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