Grandivittin (1), agasyllin (2), aegelinol benzoate (3) and felamidin (20), four natural coumarins isolated from Ferulago campestris, and several synthetic ester derivatives of aegelinol (4) were tested against four tumor cell lines. Some of them were shown to be marginally cytotoxic against the A549 lung cancer cell line.
Rosselli, S., Maggio, A.M., Faraone, N., Spadaro, V., Morris-Natschke, S.L., Bastow, K.F., et al. (2009). The cytotoxic properties of Natural Coumarins Isolated from roots of Ferulago campestris (Apiaceae) and of synthetic ester derivatives aegelinol. NATURAL PRODUCT COMMUNICATIONS, 4(12), 1701-1706.
The cytotoxic properties of Natural Coumarins Isolated from roots of Ferulago campestris (Apiaceae) and of synthetic ester derivatives aegelinol
ROSSELLI, Sergio;MAGGIO, Antonella Maria;FARAONE, Nicoletta;SPADARO, Vivienne;BRUNO, Maurizio
2009-01-01
Abstract
Grandivittin (1), agasyllin (2), aegelinol benzoate (3) and felamidin (20), four natural coumarins isolated from Ferulago campestris, and several synthetic ester derivatives of aegelinol (4) were tested against four tumor cell lines. Some of them were shown to be marginally cytotoxic against the A549 lung cancer cell line.
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