A series of derivatives of new ring system pyrido[4’,3’:4,5]pyrrolo[2,1-d] [1,2,3,5]tetrazine was obtained from moderate to excellent yields by reaction of 2-diazo-3-ethoxycarbonyl-pyrrolo[2,3- c]pyridine with alkyl- or aryl-isocyanates in dichlorometane at room temperature or at 50 °C under microwave irradiation.
DIANA, P., STAGNO, A., BARRAJA, P., CARBONE, A., MONTALBANO, A., MARTORANA, A., et al. (2009). Pyrido[4′,3′:4,5]pyrrolo[2,1-d][1,2,3,5]tetrazines, a new class of Temozolomide heteroanalogues. ARKIVOC, X, 1-11.
Pyrido[4′,3′:4,5]pyrrolo[2,1-d][1,2,3,5]tetrazines, a new class of Temozolomide heteroanalogues
DIANA, Patrizia;STAGNO, Antonina;BARRAJA, Paola;CARBONE, Anna;MONTALBANO, Alessandra;MARTORANA, Annamaria;DATTOLO, Gaetano;CIRRINCIONE, Girolamo
2009-01-01
Abstract
A series of derivatives of new ring system pyrido[4’,3’:4,5]pyrrolo[2,1-d] [1,2,3,5]tetrazine was obtained from moderate to excellent yields by reaction of 2-diazo-3-ethoxycarbonyl-pyrrolo[2,3- c]pyridine with alkyl- or aryl-isocyanates in dichlorometane at room temperature or at 50 °C under microwave irradiation.
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