Background: To assess the influence of body mass index (BMI) on the progression of dementia. Methods: Sixty elderly outpatients with dementia followed for 12 months. All patients underwent clinical, cognitive, functional, and nutritional assessment at the baseline and after 12 months. Patients were divided into 2 groups by baseline BMI (< or ≥25 kg/m2). Results: Participants with a baseline BMI ≥25 kg/m2 had significantly higher Mini-Mental State Examination (MMSE) scores (21±5.1 vs 15.9±5.5; P < .001), while clinical dementia rating (CDR) and multidimensional prognostic index (MPI) scores were similar in the 2 groups. After 12 months, the MMSE score decreased significantly in both groups compared to the baseline, while the CDR and MPI scores increased significantly for patients with a baseline BMI <25 kg/m2. Conclusion: A BMI cutoff of 25 kg/m2 could be useful for identifying frail patients with dementia who will experience a more rapid global impairment, which could be assessed adequately using multidimensional evaluation tools. © The Author(s) 2012.

Coin, A., Bolzetta, F., Rui, M., Veronese, N., Granziera, S., Girardi, A., et al. (2012). Nutritional and global indexes of progression in dementia: A 12-month prospective study. AMERICAN JOURNAL OF ALZHEIMER'S DISEASE AND OTHER DEMENTIAS, 27(7), 504-508 [10.1177/1533317512456451].

Nutritional and global indexes of progression in dementia: A 12-month prospective study

Veronese, N.;
2012-01-01

Abstract

Background: To assess the influence of body mass index (BMI) on the progression of dementia. Methods: Sixty elderly outpatients with dementia followed for 12 months. All patients underwent clinical, cognitive, functional, and nutritional assessment at the baseline and after 12 months. Patients were divided into 2 groups by baseline BMI (< or ≥25 kg/m2). Results: Participants with a baseline BMI ≥25 kg/m2 had significantly higher Mini-Mental State Examination (MMSE) scores (21±5.1 vs 15.9±5.5; P < .001), while clinical dementia rating (CDR) and multidimensional prognostic index (MPI) scores were similar in the 2 groups. After 12 months, the MMSE score decreased significantly in both groups compared to the baseline, while the CDR and MPI scores increased significantly for patients with a baseline BMI <25 kg/m2. Conclusion: A BMI cutoff of 25 kg/m2 could be useful for identifying frail patients with dementia who will experience a more rapid global impairment, which could be assessed adequately using multidimensional evaluation tools. © The Author(s) 2012.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84867651197&doi=10.1177/1533317512456451&partnerID=40&md5=b9c20593b800e11812a98eb7757d0dde
Coin, A., Bolzetta, F., Rui, M., Veronese, N., Granziera, S., Girardi, A., et al. (2012). Nutritional and global indexes of progression in dementia: A 12-month prospective study. AMERICAN JOURNAL OF ALZHEIMER'S DISEASE AND OTHER DEMENTIAS, 27(7), 504-508 [10.1177/1533317512456451].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/455337
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