BACKGROUND: The accuracy of axillary ultrasound (AUS) with fine-needle aspiration with varying patient body mass index (BMI) is still unclear. The aim of our study was to evaluate whether the US features of axillary lymph nodes changes with BMI of patients. PATIENTS AND METHODS: A retrospective review was performed involving 144 out of 270 patients with early breast cancer who underwent breast surgery with sentinel lymph node biopsy. Diagnostic efficacy of AUS in preoperative axillary nodal staging was assessed in relation to BMI. RESULTS: Negative predictive values of AUS for the overweight and obese groups were statistically significantly lower compared to the normal/underweight group (p=0.02 and p=0.003, respectively). Additionally, Spearman's correlation coefficient R between BMI and positive sentinel lymph node biopsy was 0.257, suggesting a significantly positive linear relationship between the two variables in the cohort overall. CONCLUSION: Our results demonstrate how in our cohort the negative predictive value of AUS was significantly influenced by adipose tissue and that the selection of the most suitable instrumental diagnostic technique might contribute to improving heterogeneous results.

Macaione I., Galvano A., Graceffa G., Lupo S., Latteri M., Russo A., et al. (2020). Impact of BMI on Preoperative Axillary Ultrasound Assessment in Patients With Early Breast Cancer. ANTICANCER RESEARCH, 40(12), 7083-7088 [10.21873/anticanres.14736].

Impact of BMI on Preoperative Axillary Ultrasound Assessment in Patients With Early Breast Cancer

Macaione I.;Galvano A.;Graceffa G.;Lupo S.;Latteri M.;Russo A.;Vieni S.;Cipolla C.
2020

Abstract

BACKGROUND: The accuracy of axillary ultrasound (AUS) with fine-needle aspiration with varying patient body mass index (BMI) is still unclear. The aim of our study was to evaluate whether the US features of axillary lymph nodes changes with BMI of patients. PATIENTS AND METHODS: A retrospective review was performed involving 144 out of 270 patients with early breast cancer who underwent breast surgery with sentinel lymph node biopsy. Diagnostic efficacy of AUS in preoperative axillary nodal staging was assessed in relation to BMI. RESULTS: Negative predictive values of AUS for the overweight and obese groups were statistically significantly lower compared to the normal/underweight group (p=0.02 and p=0.003, respectively). Additionally, Spearman's correlation coefficient R between BMI and positive sentinel lymph node biopsy was 0.257, suggesting a significantly positive linear relationship between the two variables in the cohort overall. CONCLUSION: Our results demonstrate how in our cohort the negative predictive value of AUS was significantly influenced by adipose tissue and that the selection of the most suitable instrumental diagnostic technique might contribute to improving heterogeneous results.
Macaione I., Galvano A., Graceffa G., Lupo S., Latteri M., Russo A., et al. (2020). Impact of BMI on Preoperative Axillary Ultrasound Assessment in Patients With Early Breast Cancer. ANTICANCER RESEARCH, 40(12), 7083-7088 [10.21873/anticanres.14736].
File in questo prodotto:
File Dimensione Formato  
Anticancer Res 2020 - Impact of BMI .pdf

Solo gestori archvio

Tipologia: Versione Editoriale
Dimensione 225.59 kB
Formato Adobe PDF
225.59 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/454075
Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 2
social impact