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EnglishFew studies assessed the associations between dietary vitamin K and depressive symptoms. We aimed to investigate the association between dietary vitamin K and depressive symptoms in a large cohort of North American People. In this cross-sectional analysis, 4,375 participants that were aged 45-79 years from the Osteoarthritis Initiative were included. Dietary vitamin K intake was collected through a semi-quantitative food frequency questionnaire and categorized in quartiles. Depressive symptoms were diagnosed using the 20-item Center for Epidemiologic Studies-Depression (CES-D) ≥ 16. To investigate the associations between vitamin K intake and depressive symptoms, logistic regression analysis were run, which adjusted for potential confounders. Overall, 437 (=10%) subjects had depressive symptoms. After adjusting for 11 confounders, people with the highest dietary vitamin K intake had lower odds of having depressive symptoms (OR = 0.58; 95%CI: 0.43-0.80). This effect was only present in people not taking vitamin D supplementation. In conclusion, higher dietary vitamin K intake was significantly associated with a lower presence of depressive symptoms, also after accounting for potential confounders. Future longitudinal research is required to explore the directionality of the association. © 2019 by the authors. Licensee MDPI, Basel, Switzerland.
Bolzetta, F., Veronese, N., Stubbs, B., Noale, M., Vaona, A., Demurtas, J., et al. (2019). The relationship between dietary vitamin k and depressive symptoms in late adulthood: A cross-sectional analysis from a large cohort study. NUTRIENTS, 11(4), 1-10.
| Data di pubblicazione: | 2019 | |
| Titolo: | The relationship between dietary vitamin k and depressive symptoms in late adulthood: A cross-sectional analysis from a large cohort study | |
| Autori: | ||
| Citazione: | Bolzetta, F., Veronese, N., Stubbs, B., Noale, M., Vaona, A., Demurtas, J., et al. (2019). The relationship between dietary vitamin k and depressive symptoms in late adulthood: A cross-sectional analysis from a large cohort study. NUTRIENTS, 11(4), 1-10. | |
| Rivista: | ||
| Digital Object Identifier (DOI): | http://dx.doi.org/10.3390/nu11040787 | |
| Abstract: | Few studies assessed the associations between dietary vitamin K and depressive symptoms. We aimed to investigate the association between dietary vitamin K and depressive symptoms in a large cohort of North American People. In this cross-sectional analysis, 4,375 participants that were aged 45-79 years from the Osteoarthritis Initiative were included. Dietary vitamin K intake was collected through a semi-quantitative food frequency questionnaire and categorized in quartiles. Depressive symptoms were diagnosed using the 20-item Center for Epidemiologic Studies-Depression (CES-D) ≥ 16. To investigate the associations between vitamin K intake and depressive symptoms, logistic regression analysis were run, which adjusted for potential confounders. Overall, 437 (=10%) subjects had depressive symptoms. After adjusting for 11 confounders, people with the highest dietary vitamin K intake had lower odds of having depressive symptoms (OR = 0.58; 95%CI: 0.43-0.80). This effect was only present in people not taking vitamin D supplementation. In conclusion, higher dietary vitamin K intake was significantly associated with a lower presence of depressive symptoms, also after accounting for potential confounders. Future longitudinal research is required to explore the directionality of the association. © 2019 by the authors. Licensee MDPI, Basel, Switzerland. | |
| URL: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064540995&doi=10.3390/nu11040787&partnerID=40&md5=94ca6cf5729c66b738f738129a670da6 | |
| Appare nelle tipologie: | 1.01 Articolo in rivista |
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| nutrients-11-00787.pdf | Versione Editoriale | Open Access Visualizza/Apri |
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