Neurodegenerative diseases (NDs) are one of major public health problems and their impact is continuously growing. Curcumin has been proposed for the treatment of several of these pathologies, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD) due to the ability of this molecule to reduce inflammation and aggregation of involved proteins. Nevertheless, the poor metabolic stability and bioavailability of curcumin reduce the possibilities of its practical use. In this review will be highlighted recent results on curcumin and curcuminoids in the search of new effective therapeutic agents against NDs, with particular emphasis on AD.
Paola Marzullo, & Silvestre Buscemi (2020). What's Curcumin's mind? The potential role of Curcuminoids in the treatment of Alzheimer's disease. EUROMEDITERRANEAN BIOMEDICAL JOURNAL.
Data di pubblicazione: | 2020 |
Titolo: | What's Curcumin's mind? The potential role of Curcuminoids in the treatment of Alzheimer's disease |
Autori: | |
Citazione: | Paola Marzullo, & Silvestre Buscemi (2020). What's Curcumin's mind? The potential role of Curcuminoids in the treatment of Alzheimer's disease. EUROMEDITERRANEAN BIOMEDICAL JOURNAL. |
Rivista: | |
Abstract: | Neurodegenerative diseases (NDs) are one of major public health problems and their impact is continuously growing. Curcumin has been proposed for the treatment of several of these pathologies, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD) due to the ability of this molecule to reduce inflammation and aggregation of involved proteins. Nevertheless, the poor metabolic stability and bioavailability of curcumin reduce the possibilities of its practical use. In this review will be highlighted recent results on curcumin and curcuminoids in the search of new effective therapeutic agents against NDs, with particular emphasis on AD. |
Settore Scientifico Disciplinare: | Settore CHIM/06 - Chimica Organica |
Appare nelle tipologie: | 1.01 Articolo in rivista |
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