The authors investigated whether repetitive transcranial magnetic stimulation (rTMS) at 1 Hz (12 minutes; 90% of motor threshold) to the primary motor cortex (M1) leads to changes in diffusion-weighted imaging (DWI). After the rTMS train, there was a temporary small restriction in diffusion within the targeted left M1 that disappeared after 5 minutes. These findings provide a physiologic correlate to the reported behavioral consequences of off-line 1-Hz rTMS and reveal the transitory nature of the effects.
Mottaghy F.M., Gangitano M., Horkan C., Chen Y., Pascual-Leone A., Schlaug G. (2003). Repetitive TMS temporarily alters brain diffusion. NEUROLOGY, 60(9), 1539-1541 [10.1212/01.WNL.0000058903.15205.46].
Repetitive TMS temporarily alters brain diffusion
Gangitano M.;
2003-01-01
Abstract
The authors investigated whether repetitive transcranial magnetic stimulation (rTMS) at 1 Hz (12 minutes; 90% of motor threshold) to the primary motor cortex (M1) leads to changes in diffusion-weighted imaging (DWI). After the rTMS train, there was a temporary small restriction in diffusion within the targeted left M1 that disappeared after 5 minutes. These findings provide a physiologic correlate to the reported behavioral consequences of off-line 1-Hz rTMS and reveal the transitory nature of the effects.
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