The role of Hippo pathway in colorectal cancer (CRC) initiation and progression has been controversial. In this issue of Cell Stem Cell, Cheung et al. (2020) shed new light on a distinct function of the transcriptional co-activator YAP as a tumor suppressor and Wnt pathway inhibitor in CRC.
Veschi V., Stassi G. (2020). The Hippo Show Must Go On: YAP Activation as a Therapeutic Strategy in Colorectal Cancer. CELL STEM CELL, 27(4), 501-502 [10.1016/j.stem.2020.09.007].
The Hippo Show Must Go On: YAP Activation as a Therapeutic Strategy in Colorectal Cancer
Veschi V.;Stassi G.
2020-01-01
Abstract
The role of Hippo pathway in colorectal cancer (CRC) initiation and progression has been controversial. In this issue of Cell Stem Cell, Cheung et al. (2020) shed new light on a distinct function of the transcriptional co-activator YAP as a tumor suppressor and Wnt pathway inhibitor in CRC.
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