Haemopoietic effects of 7 alpha, 17 beta Dimethyltestosterone

D. 'Alessandre N.,; Gebbia, N; Biondo, F; Campio, L; Leto, G; Tumminello, F; Rausa, L

doi:10.1016/S0031-6989(79)80062-4

Some haematic parameters were investigated in female COBS mice treated with 7 alpha, 17 beta Dimethyltestcsterone (DMT). The drug causes an increase of circulating platelets in normal mice. Bone marrow graft from DMT-treated donors facilitates in irradiated mice repopulation of white blood cells and platelets but lowers % survival. These data are interpreted on the basis of a commitment and a loss of self-maintenance induced by DMT on CFUs compartment. © 1979 The Italian Pharmacological Society.

D.'Alessandre N., Gebbia N., Biondo F., Campio L., Leto G., Tumminello F., et al. (1979). Haemopoietic effects of 7 alpha, 17 beta Dimethyltestosterone. PHARMACOLOGICAL RESEARCH COMMUNICATIONS, 11(2), 81-94.

Data di pubblicazione:	1979
Titolo:	Haemopoietic effects of 7 alpha, 17 beta Dimethyltestosterone
Autori:	D. 'Alessandre N. GEBBIA, Nicolo' Biondo F. [Methodology] Campio L. LETO, Gaetano [Investigation] Tumminello F. [Investigation] RAUSA, Luciano mostra contributor esterni nascondi contributor esterni
Citazione:	D.'Alessandre N., Gebbia N., Biondo F., Campio L., Leto G., Tumminello F., et al. (1979). Haemopoietic effects of 7 alpha, 17 beta Dimethyltestosterone. PHARMACOLOGICAL RESEARCH COMMUNICATIONS, 11(2), 81-94.
Rivista:	PHARMACOLOGICAL RESEARCH COMMUNICATIONS
Digital Object Identifier (DOI):	http://dx.doi.org/10.1016/S0031-6989(79)80062-4
Abstract:	Some haematic parameters were investigated in female COBS mice treated with 7 alpha, 17 beta Dimethyltestcsterone (DMT). The drug causes an increase of circulating platelets in normal mice. Bone marrow graft from DMT-treated donors facilitates in irradiated mice repopulation of white blood cells and platelets but lowers % survival. These data are interpreted on the basis of a commitment and a loss of self-maintenance induced by DMT on CFUs compartment. © 1979 The Italian Pharmacological Society.
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http://hdl.handle.net/10447/434953

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