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EnglishHormones, i.e., the products of specialized endocrine cells which spread throughout the body via the bloodstream, control the normal development and growth of organisms at the embryo-fetal stage and, in adult life, regulate, integrate, and coordinate a range of different physiological processes which concern virtually all body tissues. They exert their biological effects by interacting with either surface or intracellular receptors, thereby activating signalization pathways [1]. For example, steroid hormones, such as those released by the adrenal glands, testes and ovaries, once freely crossed through the plasmalemma, bind to receptors that act as ligand-dependent transcriptional regulators and influence the expression of a plethora of target genes responsible for diversified biological responses, including sexual differentiation, osmoregulation, metabolism and developmental roles in various fetal systems among others [2,3].
Luparello C (2020). Hormone Involvement in Tissue Development, Physiology and Oncogenesis: A Preface to the Special Issue. CANCERS, 12(9), 1-2.
| Data di pubblicazione: | 2020 |
| Titolo: | Hormone Involvement in Tissue Development, Physiology and Oncogenesis: A Preface to the Special Issue |
| Autori: | LUPARELLO, Claudio (Corresponding) |
| Citazione: | Luparello C (2020). Hormone Involvement in Tissue Development, Physiology and Oncogenesis: A Preface to the Special Issue. CANCERS, 12(9), 1-2. |
| Rivista: | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.3390/cancers12092642 |
| Abstract: | Hormones, i.e., the products of specialized endocrine cells which spread throughout the body via the bloodstream, control the normal development and growth of organisms at the embryo-fetal stage and, in adult life, regulate, integrate, and coordinate a range of different physiological processes which concern virtually all body tissues. They exert their biological effects by interacting with either surface or intracellular receptors, thereby activating signalization pathways [1]. For example, steroid hormones, such as those released by the adrenal glands, testes and ovaries, once freely crossed through the plasmalemma, bind to receptors that act as ligand-dependent transcriptional regulators and influence the expression of a plethora of target genes responsible for diversified biological responses, including sexual differentiation, osmoregulation, metabolism and developmental roles in various fetal systems among others [2,3]. |
| Settore Scientifico Disciplinare: | Settore BIO/06 - Anatomia Comparata E Citologia |
| Appare nelle tipologie: | 1.01 Articolo in rivista |
File in questo prodotto:
| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| cancers-12-02642.pdf | Post-print | Open Access Visualizza/Apri |
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