Hormones, i.e., the products of specialized endocrine cells which spread throughout the body via the bloodstream, control the normal development and growth of organisms at the embryo-fetal stage and, in adult life, regulate, integrate, and coordinate a range of different physiological processes which concern virtually all body tissues. They exert their biological effects by interacting with either surface or intracellular receptors, thereby activating signalization pathways [1]. For example, steroid hormones, such as those released by the adrenal glands, testes and ovaries, once freely crossed through the plasmalemma, bind to receptors that act as ligand-dependent transcriptional regulators and influence the expression of a plethora of target genes responsible for diversified biological responses, including sexual differentiation, osmoregulation, metabolism and developmental roles in various fetal systems among others [2,3].

Luparello C (2020). Hormone Involvement in Tissue Development, Physiology and Oncogenesis: A Preface to the Special Issue. CANCERS, 12(9), 1-2 [10.3390/cancers12092642].

Hormone Involvement in Tissue Development, Physiology and Oncogenesis: A Preface to the Special Issue

Luparello C
2020-01-01

Abstract

Hormones, i.e., the products of specialized endocrine cells which spread throughout the body via the bloodstream, control the normal development and growth of organisms at the embryo-fetal stage and, in adult life, regulate, integrate, and coordinate a range of different physiological processes which concern virtually all body tissues. They exert their biological effects by interacting with either surface or intracellular receptors, thereby activating signalization pathways [1]. For example, steroid hormones, such as those released by the adrenal glands, testes and ovaries, once freely crossed through the plasmalemma, bind to receptors that act as ligand-dependent transcriptional regulators and influence the expression of a plethora of target genes responsible for diversified biological responses, including sexual differentiation, osmoregulation, metabolism and developmental roles in various fetal systems among others [2,3].
Settore BIO/06 - Anatomia Comparata E Citologia
Luparello C (2020). Hormone Involvement in Tissue Development, Physiology and Oncogenesis: A Preface to the Special Issue. CANCERS, 12(9), 1-2 [10.3390/cancers12092642].
File in questo prodotto:
File Dimensione Formato  
cancers-12-02642.pdf

accesso aperto

Tipologia: Post-print
Dimensione 161.12 kB
Formato Adobe PDF
161.12 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/432384
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
social impact