Performance of existing definitions and tests for the diagnosis of invasive aspergillosis in critically ill, adult patients: A systematic review with qualitative evidence synthesis

Bassetti, M.; Giacobbe, D.R.; Grecchi, C.; Rebuffi, C.; Zuccaro, V.; Scudeller, L.; Akova, M.; Alastruey-Izquierdo, A.; Arikan-Akdagli, S.; Azoulay, E.; Blot, S.; A Cornely, O.; Lass-Flörl, C.; Koehler, P.; Cuenca-Estrella, M.; W De Lange, D.; G De Rosa, F.; J De Waele, J.; Dimopoulos, G.; Garnacho-Montero, J.; Hoenigl, M.; S Kanj, S.; Lamoth, F.; Maertens, J.; Martin-Loeches, I.; Muñoz, P.; J Kullberg, B.; Agvald-Ohman, C.; Poulakou, G.; Rello, J.; Righi, E.; Sanguinetti, M.; S Taccone, F.; Timsit, J.; Torres, A.; A Vazquez, J.; Wauters, J.; Calandra, T.; Asperges, E.; Tejada, S.; Lebihan, C.; Karaiskos, I.; Peghin, M.; L Mortensen, K.; Vena, A.; Cortegiani, A.; Mercier, T.

doi:10.1016/j.jinf.2020.03.065

To summarize the available evidence on the diagnostic performance for invasive aspergillosis (IA) in non-hematological, non-solid organ transplantation critically ill patients of the following: (i) existing definitions of IA (developed either for classical immunocompromised populations or for non-immunocompromised critically ill patients); (ii) laboratory tests; (iii) radiology tests.

M, B., D R, G., C, G., C, R., V, Z., L, S., et al. (2020). Performance of existing definitions and tests for the diagnosis of invasive aspergillosis in critically ill, adult patients: A systematic review with qualitative evidence synthesis. JOURNAL OF INFECTION [10.1016/j.jinf.2020.03.065].