Mediterranean spotted fever (MSF) is an infectious disease endemic in the southern regions of Italy, with an incidence of about 400 cases/year. The bacteria responsible of the disease is Rickettsia conorii, transmitted to humans by Rhipicephalus sanguineus, the common dog tick. The infection usually manifests with a characteristic symptomatologic triad: fever, exanthema and the so called tache noire, which is the typical eschar at the site of the tick bite. Immunoglobulin M (IgM) and IgG enzymelinked immunosorbent assay and the gold standard micro-immunofluorescent assay, allow serological diagnosis. We report the case of a man suffering from MSF, whose atypical presentation and false-negative diagnostic tests delayed consistently diagnosis and therapy. Afterwards we review the literature about this topic.

Mansueto P., Seidita A., Bongiovi A., Catalano T., Pirrone G., Cusimano C., et al. (2016). Multiple organ failure as onset of mediterranean spotted fever: A review based on a case. ITALIAN JOURNAL OF MEDICINE, 10(3), 195-201 [10.4081/itjm.2016.625].

Multiple organ failure as onset of mediterranean spotted fever: A review based on a case

Mansueto P.;Seidita A.;Carroccio A.
2016

Abstract

Mediterranean spotted fever (MSF) is an infectious disease endemic in the southern regions of Italy, with an incidence of about 400 cases/year. The bacteria responsible of the disease is Rickettsia conorii, transmitted to humans by Rhipicephalus sanguineus, the common dog tick. The infection usually manifests with a characteristic symptomatologic triad: fever, exanthema and the so called tache noire, which is the typical eschar at the site of the tick bite. Immunoglobulin M (IgM) and IgG enzymelinked immunosorbent assay and the gold standard micro-immunofluorescent assay, allow serological diagnosis. We report the case of a man suffering from MSF, whose atypical presentation and false-negative diagnostic tests delayed consistently diagnosis and therapy. Afterwards we review the literature about this topic.
Settore MED/09 - Medicina Interna
Mansueto P., Seidita A., Bongiovi A., Catalano T., Pirrone G., Cusimano C., et al. (2016). Multiple organ failure as onset of mediterranean spotted fever: A review based on a case. ITALIAN JOURNAL OF MEDICINE, 10(3), 195-201 [10.4081/itjm.2016.625].
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/415081
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