Hypovitaminosis D is a worldwide disorder, with a high prevalence in the general population of both Western and developing countries. In HIV patients, several studies have linked vitamin D status with bone disease, neurocognitive impairment, depression, cardiovascular disease, high blood pressure, metabolic syndrome, type 2 diabetes mellitus, infections, autoimmune diseases like type 1 diabetes mellitus, and cancer. In this review, we focus on the most recent epidemiological and experimental data dealing with the relationship between vitamin D defficiency and HIV infection. We analysed the extent of the problem, pathogenic mechanisms, clinical implications, and potential benefits of vitamin D supplementation in HIV-infected subjects.

Mansueto, P., Seidita, A., Vitale, G., Gangemi, S., Iaria, C., Cascio, A. (2015). Vitamin D deficiency in HIV infection: Not only a bone disorder [10.1155/2015/735615].

Vitamin D deficiency in HIV infection: Not only a bone disorder

MANSUETO, Pasquale;SEIDITA, Aurelio;CASCIO, ANTONIO
2015-01-01

Abstract

Hypovitaminosis D is a worldwide disorder, with a high prevalence in the general population of both Western and developing countries. In HIV patients, several studies have linked vitamin D status with bone disease, neurocognitive impairment, depression, cardiovascular disease, high blood pressure, metabolic syndrome, type 2 diabetes mellitus, infections, autoimmune diseases like type 1 diabetes mellitus, and cancer. In this review, we focus on the most recent epidemiological and experimental data dealing with the relationship between vitamin D defficiency and HIV infection. We analysed the extent of the problem, pathogenic mechanisms, clinical implications, and potential benefits of vitamin D supplementation in HIV-infected subjects.
Settore MED/09 - Medicina Interna
Mansueto, P., Seidita, A., Vitale, G., Gangemi, S., Iaria, C., Cascio, A. (2015). Vitamin D deficiency in HIV infection: Not only a bone disorder [10.1155/2015/735615].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/414988
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