Hypovitaminosis D is a worldwide disorder, with a high prevalence in the general population of both Western and developing countries. In HIV patients, several studies have linked vitamin D status with bone disease, neurocognitive impairment, depression, cardiovascular disease, high blood pressure, metabolic syndrome, type 2 diabetes mellitus, infections, autoimmune diseases like type 1 diabetes mellitus, and cancer. In this review, we focus on the most recent epidemiological and experimental data dealing with the relationship between vitamin D defficiency and HIV infection. We analysed the extent of the problem, pathogenic mechanisms, clinical implications, and potential benefits of vitamin D supplementation in HIV-infected subjects.
Mansueto, P., Seidita, A., Vitale, G., Gangemi, S., Iaria, C., & Cascio, A. (2015). Vitamin D deficiency in HIV infection: Not only a bone disorder [10.1155/2015/735615].
Data di pubblicazione: | 2015 | |
Titolo: | Vitamin D deficiency in HIV infection: Not only a bone disorder | |
Autori: | ||
Citazione: | Mansueto, P., Seidita, A., Vitale, G., Gangemi, S., Iaria, C., & Cascio, A. (2015). Vitamin D deficiency in HIV infection: Not only a bone disorder [10.1155/2015/735615]. | |
Rivista: | ||
Digital Object Identifier (DOI): | http://dx.doi.org/10.1155/2015/735615 | |
Abstract: | Hypovitaminosis D is a worldwide disorder, with a high prevalence in the general population of both Western and developing countries. In HIV patients, several studies have linked vitamin D status with bone disease, neurocognitive impairment, depression, cardiovascular disease, high blood pressure, metabolic syndrome, type 2 diabetes mellitus, infections, autoimmune diseases like type 1 diabetes mellitus, and cancer. In this review, we focus on the most recent epidemiological and experimental data dealing with the relationship between vitamin D defficiency and HIV infection. We analysed the extent of the problem, pathogenic mechanisms, clinical implications, and potential benefits of vitamin D supplementation in HIV-infected subjects. | |
Settore Scientifico Disciplinare: | Settore MED/09 - Medicina Interna | |
Appare nelle tipologie: | 1.09 Review essay (rassegna critica) |
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