Cannabinoid consumption during pregnancy has been increasing on the wave of the broad-based legalisation of cannabis in Western countries, raising concern about the putative detrimental outcomes on foetal neurodevelopment. Indeed, since the endocannabinoid system regulates synaptic plasticity, emotional and cognitive processes from early stages of life interfering with it and other excitability endogenous modulators, such as neuropeptide Y (NPY), might contribute to the occurrence of a vulnerable phenotype later in life.

Brancato, A., Castelli, V., Lavanco, G., Marino, R.A.M., Cannizzaro, C. (2020). In utero Δ9-tetrahydrocannabinol exposure confers vulnerability towards cognitive impairments and alcohol drinking in the adolescent offspring: Is there a role for neuropeptide Y?. JOURNAL OF PSYCHOPHARMACOLOGY, 269881120916135 [10.1177/0269881120916135].

In utero Δ9-tetrahydrocannabinol exposure confers vulnerability towards cognitive impairments and alcohol drinking in the adolescent offspring: Is there a role for neuropeptide Y?

Brancato, Anna;Castelli, Valentina;Lavanco, Gianluca;Cannizzaro, Carla
2020-01-01

Abstract

Cannabinoid consumption during pregnancy has been increasing on the wave of the broad-based legalisation of cannabis in Western countries, raising concern about the putative detrimental outcomes on foetal neurodevelopment. Indeed, since the endocannabinoid system regulates synaptic plasticity, emotional and cognitive processes from early stages of life interfering with it and other excitability endogenous modulators, such as neuropeptide Y (NPY), might contribute to the occurrence of a vulnerable phenotype later in life.
Settore BIO/14 - Farmacologia
Brancato, A., Castelli, V., Lavanco, G., Marino, R.A.M., Cannizzaro, C. (2020). In utero Δ9-tetrahydrocannabinol exposure confers vulnerability towards cognitive impairments and alcohol drinking in the adolescent offspring: Is there a role for neuropeptide Y?. JOURNAL OF PSYCHOPHARMACOLOGY, 269881120916135 [10.1177/0269881120916135].
File in questo prodotto:
File Dimensione Formato  
Brancato 2020.pdf

Solo gestori archvio

Tipologia: Pre-print
Dimensione 5.67 MB
Formato Adobe PDF
5.67 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/412560
Citazioni
  • ???jsp.display-item.citation.pmc??? 8
  • Scopus 11
  • ???jsp.display-item.citation.isi??? 11
social impact