Core/shell gel beads with embedded halloysite nanotubes for controlled drug release

Lisuzzo, L; Cavallaro, G; Parisi, F; Milioto, S; Fakhrullin, R; Lazzara, G

doi:10.3390/COATINGS9020070

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The use of nanocomposites based on biopolymers and nanoparticles for controlled drug release is an attractive notion. We used halloysite nanotubes that were promising candidates for the loading and release of active molecules due to their hollow cavity. Gel beads based on chitosan with uniformly dispersed halloysite nanotubes were obtained by a dropping method. Alginate was used to generate a coating layer over the hybrid gel beads. This proposed procedure succeeded in controlling the morphology at the mesoscale and it had a relevant effect on the release profile of the model drug from the nanotube cavity.

Data di pubblicazione:	2019
Titolo:	Core/shell gel beads with embedded halloysite nanotubes for controlled drug release
Autori:	LISUZZO, Lorenzo [Investigation] CAVALLARO, Giuseppe [Conceptualization] PARISI, Filippo [Conceptualization] MILIOTO, Stefana [Conceptualization] Fakhrullin R. LAZZARA, Giuseppe [Conceptualization] (Corresponding) mostra contributor esterni nascondi contributor esterni
Citazione:	Lisuzzo, L., Cavallaro, G., Parisi, F., Milioto, S., Fakhrullin, R., & Lazzara, G. (2019). Core/shell gel beads with embedded halloysite nanotubes for controlled drug release. COATINGS, 9(2), 70-77.
Rivista:	COATINGS
Digital Object Identifier (DOI):	http://dx.doi.org/10.3390/COATINGS9020070
Abstract:	The use of nanocomposites based on biopolymers and nanoparticles for controlled drug release is an attractive notion. We used halloysite nanotubes that were promising candidates for the loading and release of active molecules due to their hollow cavity. Gel beads based on chitosan with uniformly dispersed halloysite nanotubes were obtained by a dropping method. Alginate was used to generate a coating layer over the hybrid gel beads. This proposed procedure succeeded in controlling the morphology at the mesoscale and it had a relevant effect on the release profile of the model drug from the nanotube cavity.
URL:	https://res.mdpi.com/coatings/coatings-09-00070/article_deploy/coatings-09-00070-v3.pdf?filename=&attachment=1
Appare nelle tipologie:	1.01 Articolo in rivista

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Utilizza questo identificativo per citare o creare un link a questo documento:
http://hdl.handle.net/10447/391560

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