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EnglishFactor VIII (FVIII) is indicated for the prevention or treatment of bleeding in patients with hemophilia A. FVIII product stability under high and fluctuating temperatures is important, particularly for patients who reside in, or travel to, regions with high ambient temperatures, as they may remove their product from the refrigerator and return it, unused, multiple times. We evaluated the effect of variable temperature storage conditions, including up to 40 °C, on the stability of the recombinant FVIII product, turoctocog alfa.
Napolitano, M., & Nøhr, A. (2019). The Effect of Fluctuating Temperature on the Stability of Turoctocog Alfa for Hemophilia A. DRUGS IN R&D.
| Data di pubblicazione: | 2019 |
| Titolo: | The Effect of Fluctuating Temperature on the Stability of Turoctocog Alfa for Hemophilia A |
| Autori: | |
| Citazione: | Napolitano, M., & Nøhr, A. (2019). The Effect of Fluctuating Temperature on the Stability of Turoctocog Alfa for Hemophilia A. DRUGS IN R&D. |
| Rivista: | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1007/s40268-019-00290-3 |
| Abstract: | Factor VIII (FVIII) is indicated for the prevention or treatment of bleeding in patients with hemophilia A. FVIII product stability under high and fluctuating temperatures is important, particularly for patients who reside in, or travel to, regions with high ambient temperatures, as they may remove their product from the refrigerator and return it, unused, multiple times. We evaluated the effect of variable temperature storage conditions, including up to 40 °C, on the stability of the recombinant FVIII product, turoctocog alfa. |
| Appare nelle tipologie: | 1.01 Articolo in rivista |
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| File | Descrizione | Tipologia | Licenza | |
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| ArticoloN8.pdf | Published article | Post-print | Open Access Visualizza/Apri |
http://hdl.handle.net/10447/386101
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