The number of Left Ventricular Assist Devices (LVADs) implanted each year is rising. Nevertheless, there are minimal data on device acceptance after LVAD implant, and on its relationship with patient-reported outcomes. We designed a cross-sectional study to address this knowledge gap and test the hypothesis that low device acceptance is associated with poorer quality of life, depression and anxiety. Self-report questionnaires were administered to assess quality of life (12-item Kansas City Cardiomyopathy Questionnaire quality of life subscale), level of anxiety (7-item Generalized Anxiety Disorder; GAD-7), level of depression (9-item Patient Health Questionnaire; PHQ-9) and device acceptance (Florida Patient Acceptance Survey; FPAS) to 101 consecutive patients presenting to LVAD clinic. Regression analysis showed a strong correlation between device acceptance and both psychological distress (p < 0.001) and quality of life (p < 0.001). Analysis of the sub-scales of the FPAS showed that patients had significant body image concerns, but return to function and device-related distress were the main drivers of the observed correlation between device acceptance and patient well-being. Younger age was associated with lower device acceptance (r = 0.36, p < 0.001) and lower quality of life (r = 0.54, p < 0.001). These findings suggest that interventions targeting device acceptance should be explored to improve outcomes in LVAD recipients.
|Data di pubblicazione:||2019|
|Titolo:||Relationship between device acceptance and patient-reported outcomes in Left Ventricular Assist Device (LVAD) recipients|
|Citazione:||Tosto, C., Adamo, L., Craddock, H., Di Blasi, M., Girgenti, R., Clemenza, F., et al. (2019). Relationship between device acceptance and patient-reported outcomes in Left Ventricular Assist Device (LVAD) recipients. SCIENTIFIC REPORTS, 9(1), 1-8.|
|Digital Object Identifier (DOI):||10.1038/s41598-019-47324-z|
|Appare nelle tipologie:||1.01 Articolo in rivista|
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|Tosto_et_al-2019 Relationship between device acceptance and patient-reported outcomes in Left Ventricular Assist Device (LVAD) recipients.pdf||Versione Editoriale||Open Access Visualizza/Apri|