Targeting quality of life in asthmatic children: The MyTEP pilot randomized trial

Laura, M; Ferrante, G; Cilluffo, G; Manuel, G; Marco, A; Dario La Guardia,; Mario, A; Velia, M; Rosalia Paola Gagliardo,; Matteo, B; Stefania La Grutta,

doi:10.1016/j.rmed.2019.05.008

Background: Quality of life (QoL) is an important outcome in the management of children with asthma. Mobile Health (m-Health) and Therapeutic Education Programs (TEPs) are increasingly recognized as essential components of pediatric asthma management to improve disease outcomes. Objective: To evaluate the effect of an education program (MyTherapeutic Education Program, MyTEP) that couples multidisciplinary TEP intervention with an m-Health Program (mHP) in improving QoL in asthmatic children. Methods: This single-center study employed a nonblinded randomized clinical trial design. Italian-speaking children (6–11 years) with mild-moderate asthma were eligible for participation. Participants were randomly paired 1:1 with a control group that received mHP (smartphone app) or an intervention group that received MyTEP (TEP plus a smartphone app). Patients were followed up for 3 months. Descriptive statistics, Least Square (LS) mean change and Generalized Linear Mixed model were used for analysis. Results: Fifty patients were enrolled. The Pediatric Asthma Quality of Life Questionnaire (PAQLQ) score improved in both MyTEP (p = 0.014) and mHP (p = 0.046) with the minimally clinically significant difference of ⩾0.5 points reached in 23% of MyTEP and in 16% of mHP. Changes in PAQLQ scores were significantly greater in MyTEP than in mHP (LS mean difference: 0.269 p = 0.05). PAQLQ score was: positively associated with MyTEP (p = 0.023) and study time (p = 0.002); and inversely associated with current passive smoke exposure (p = 0.003). Conclusion: Despite the small sample size and short observation period, this study demonstrated that implementing a multidisciplinary TEP with an m-Health program results in gains in QoL of children with asthma.

Montalbano, L., Ferrante, G., Cilluffo, G., Gentile, M., Arrigo, M., La Guardia, D., et al. (2019). Targeting quality of life in asthmatic children: The MyTEP pilot randomized trial. RESPIRATORY MEDICINE, 153, 14-19 [10.1016/j.rmed.2019.05.008].

Data di pubblicazione:	2019
Titolo:	Targeting quality of life in asthmatic children: The MyTEP pilot randomized trial
Autori:	Laura Montalbano FERRANTE, Giuliana Cilluffo, Giovanna Manuel Gentile Marco Arrigo Dario La Guardia Mario Allegra Velia Malizia Rosalia Paola Gagliardo Matteo Bonini Stefania La Grutta mostra contributor esterni nascondi contributor esterni
Citazione:	Montalbano, L., Ferrante, G., Cilluffo, G., Gentile, M., Arrigo, M., La Guardia, D., et al. (2019). Targeting quality of life in asthmatic children: The MyTEP pilot randomized trial. RESPIRATORY MEDICINE, 153, 14-19 [10.1016/j.rmed.2019.05.008].
Rivista:	RESPIRATORY MEDICINE
Digital Object Identifier (DOI):	http://dx.doi.org/10.1016/j.rmed.2019.05.008
Abstract:	Background: Quality of life (QoL) is an important outcome in the management of children with asthma. Mobile Health (m-Health) and Therapeutic Education Programs (TEPs) are increasingly recognized as essential components of pediatric asthma management to improve disease outcomes. Objective: To evaluate the effect of an education program (MyTherapeutic Education Program, MyTEP) that couples multidisciplinary TEP intervention with an m-Health Program (mHP) in improving QoL in asthmatic children. Methods: This single-center study employed a nonblinded randomized clinical trial design. Italian-speaking children (6–11 years) with mild-moderate asthma were eligible for participation. Participants were randomly paired 1:1 with a control group that received mHP (smartphone app) or an intervention group that received MyTEP (TEP plus a smartphone app). Patients were followed up for 3 months. Descriptive statistics, Least Square (LS) mean change and Generalized Linear Mixed model were used for analysis. Results: Fifty patients were enrolled. The Pediatric Asthma Quality of Life Questionnaire (PAQLQ) score improved in both MyTEP (p = 0.014) and mHP (p = 0.046) with the minimally clinically significant difference of ⩾0.5 points reached in 23% of MyTEP and in 16% of mHP. Changes in PAQLQ scores were significantly greater in MyTEP than in mHP (LS mean difference: 0.269 p = 0.05). PAQLQ score was: positively associated with MyTEP (p = 0.023) and study time (p = 0.002); and inversely associated with current passive smoke exposure (p = 0.003). Conclusion: Despite the small sample size and short observation period, this study demonstrated that implementing a multidisciplinary TEP with an m-Health program results in gains in QoL of children with asthma.
Appare nelle tipologie:	1.01 Articolo in rivista

File in questo prodotto:

File	Descrizione	Tipologia	Licenza
Montalbano_Res Med 2019.pdf		N/A		Administrator Richiedi una copia

Utilizza questo identificativo per citare o creare un link a questo documento:
http://hdl.handle.net/10447/357205

Citazioni

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Archivio istituzionale della ricerca dell'Università degli Studi di Palermo

File in questo prodotto: