Inflammatory bowel disease is a complex chronic inflammatory disease of the human gut with no clear etiology. Traditionally, dysregulated adaptive immune responses play an important role even though accumulating evidence suggest a role also for innate immunity. Because of the well known plasticity of γδ T cells, we investigated their percentage, phenotypical features and effector functions in the intestinal mucosa of early onset and long standing IBD patients, as compared to healthy subjects.

Lo Presti, E., Di Mitri, R., Mocciaro, F., Di Stefano, A.B., Scibetta, N., Unti, E., et al. (2019). Characterization of γδ T cells in intestinal mucosa from patients with early onset or long standing inflammatory bowel disease and their correlation with clinical status. JOURNAL OF CROHN'S AND COLITIS, 1-11 [10.1093/ecco-jcc/jjz015].

Characterization of γδ T cells in intestinal mucosa from patients with early onset or long standing inflammatory bowel disease and their correlation with clinical status

Lo Presti, Elena;Di Mitri, Roberto;Mocciaro, Filippo;Di Stefano, Anna Barbara;Unti, Elettra;Cicero, Giuseppe;PECORARO, Giulia Maria;Conte, Elisabetta;Dieli, Francesco;Meraviglia, Serena
2019

Abstract

Inflammatory bowel disease is a complex chronic inflammatory disease of the human gut with no clear etiology. Traditionally, dysregulated adaptive immune responses play an important role even though accumulating evidence suggest a role also for innate immunity. Because of the well known plasticity of γδ T cells, we investigated their percentage, phenotypical features and effector functions in the intestinal mucosa of early onset and long standing IBD patients, as compared to healthy subjects.
Lo Presti, E., Di Mitri, R., Mocciaro, F., Di Stefano, A.B., Scibetta, N., Unti, E., et al. (2019). Characterization of γδ T cells in intestinal mucosa from patients with early onset or long standing inflammatory bowel disease and their correlation with clinical status. JOURNAL OF CROHN'S AND COLITIS, 1-11 [10.1093/ecco-jcc/jjz015].
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/356649
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