This case-report shows that high frequency repetitive Transcranial Magnetic Stimulation (hf-rTMS), applied to the left prefrontal cortex, may improve the linguistic skills in Primary Progressive Aphasia (PPA). The patient's performance was evaluated on a battery of language production and memory span tasks, before and after two hf-rTMS treatments and one SHAM treatment. We observed a significant and lasting improvement of the patient's performance on verb production following the application of hf-rTMS versus Baseline and SHAM conditions. This finding suggests that hf-rTMS may directly strengthen the neural connections within an area of metabolic dysfunction and encourages the use of rTMS as an alternative therapeutic tool for neurodegenerative forms of aphasia.

Finocchiaro C, Maimone M, Brighina F, Piccoli T, Giglia G, Fierro B (2006). A case study of primary progressive aphasia: Improvement on verbs after rTMS treatment. NEUROCASE, 12(6), 317-321 [10.1080/13554790601126203].

A case study of primary progressive aphasia: Improvement on verbs after rTMS treatment

BRIGHINA, Filippo;PICCOLI, Tommaso;GIGLIA, Giuseppe;FIERRO, Brigida
2006-01-01

Abstract

This case-report shows that high frequency repetitive Transcranial Magnetic Stimulation (hf-rTMS), applied to the left prefrontal cortex, may improve the linguistic skills in Primary Progressive Aphasia (PPA). The patient's performance was evaluated on a battery of language production and memory span tasks, before and after two hf-rTMS treatments and one SHAM treatment. We observed a significant and lasting improvement of the patient's performance on verb production following the application of hf-rTMS versus Baseline and SHAM conditions. This finding suggests that hf-rTMS may directly strengthen the neural connections within an area of metabolic dysfunction and encourages the use of rTMS as an alternative therapeutic tool for neurodegenerative forms of aphasia.
2006
Settore MED/26 - Neurologia
Settore BIO/09 - Fisiologia
Settore M-PSI/02 - Psicobiologia E Psicologia Fisiologica
Finocchiaro C, Maimone M, Brighina F, Piccoli T, Giglia G, Fierro B (2006). A case study of primary progressive aphasia: Improvement on verbs after rTMS treatment. NEUROCASE, 12(6), 317-321 [10.1080/13554790601126203].
File in questo prodotto:
File Dimensione Formato  
Finocchiaro et al_neurocase2006.pdf

Solo gestori archvio

Dimensione 5.54 MB
Formato Adobe PDF
5.54 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/35631
Citazioni
  • ???jsp.display-item.citation.pmc??? 22
  • Scopus 71
  • ???jsp.display-item.citation.isi??? 57
social impact