Introduction: Celiac disease (CD) is an immune-mediated disorder associated with gluten exposure in genetically predisposed subjects. Areas covered: Infectious disease is one of the causes of morbidity and mortality in CD patients. Invasive streptococcus pneumoniae (pneumococcus) is a particularly dangerous morbid condition in both the general population and celiac patients. Pneumococcal vaccination is the most effective means for its prevention. Expert opinion: In CD, evaluation of spleen function should be useful to select patients who may benefit from vaccination to reduce the risk of pneumococcal disease. Different strategies could be employed: physicians could search for signs of hyposplenism on peripheral blood smear or abdominal ultrasound. However, the best strategy to identify which patients will benefit from pneumococcal vaccination has not yet been defined.

Casella G, I.F. (2019). Pneumococcal vaccination in celiac disease. EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY [10.1080/17474124.2019.1607295].

Pneumococcal vaccination in celiac disease

Mansueto P;Carroccio A.
Ultimo
2019-01-01

Abstract

Introduction: Celiac disease (CD) is an immune-mediated disorder associated with gluten exposure in genetically predisposed subjects. Areas covered: Infectious disease is one of the causes of morbidity and mortality in CD patients. Invasive streptococcus pneumoniae (pneumococcus) is a particularly dangerous morbid condition in both the general population and celiac patients. Pneumococcal vaccination is the most effective means for its prevention. Expert opinion: In CD, evaluation of spleen function should be useful to select patients who may benefit from vaccination to reduce the risk of pneumococcal disease. Different strategies could be employed: physicians could search for signs of hyposplenism on peripheral blood smear or abdominal ultrasound. However, the best strategy to identify which patients will benefit from pneumococcal vaccination has not yet been defined.
2019
Settore MED/09 - Medicina Interna
Casella G, I.F. (2019). Pneumococcal vaccination in celiac disease. EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY [10.1080/17474124.2019.1607295].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/352992
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