Objective: To investigate the difference of long-term amenorrhea rate in patients with menorrhagia treated by endometrial laser intrauterine thermal therapy (ELITT), a new nonhysteroscopic endometrial ablation proce- dure, versus transcervical hysteroscopic endometrial resection (TCRE). Design: Randomized clinical study. Healthy volunteers in an academic research environment. Setting: Academic teaching hospital. Patient(s): Premenopausal women with abnormal uterine bleeding. Intervention(s): Fifty-eight patients were treated with the ELITT procedure and 58 patients with TCRE; both groups were treated with GnRH agonists before the procedure. Main Outcome Measure(s): Bleeding status and patient satisfaction after treatment were evaluated as well as the intraoperative complication rate. Result(s): At 12 months, the amenorrhea rate was 56% in the ELITT group and 23% in the TCRE group. At 36 months, the figures were 61% for ELITT and 24% for TCRE. No significant complications were recorded for either procedure. Conclusion(s): Results of this randomized study demonstrate that both procedures are equally effective in the treatment of menorrhagia. However, the ELITT procedure has proven to be superior in inducing amenorrhea.

PERINO A, CASTELLI A, CUCINELLA G, BIONDO A, PANE A, & VENEZIA R (2004). A randomized comparison of endometrial laser intrauterine thermotherapy and hysteroscopic endometrial resection. FERTILITY AND STERILITY, 82(3), 731-734 [10.1016/j.fertnstert.2004.01.045].

A randomized comparison of endometrial laser intrauterine thermotherapy and hysteroscopic endometrial resection

PERINO, Antonino;CASTELLI, Antonio;CUCINELLA, Gaspare;VENEZIA, Renato
2004

Abstract

Objective: To investigate the difference of long-term amenorrhea rate in patients with menorrhagia treated by endometrial laser intrauterine thermal therapy (ELITT), a new nonhysteroscopic endometrial ablation proce- dure, versus transcervical hysteroscopic endometrial resection (TCRE). Design: Randomized clinical study. Healthy volunteers in an academic research environment. Setting: Academic teaching hospital. Patient(s): Premenopausal women with abnormal uterine bleeding. Intervention(s): Fifty-eight patients were treated with the ELITT procedure and 58 patients with TCRE; both groups were treated with GnRH agonists before the procedure. Main Outcome Measure(s): Bleeding status and patient satisfaction after treatment were evaluated as well as the intraoperative complication rate. Result(s): At 12 months, the amenorrhea rate was 56% in the ELITT group and 23% in the TCRE group. At 36 months, the figures were 61% for ELITT and 24% for TCRE. No significant complications were recorded for either procedure. Conclusion(s): Results of this randomized study demonstrate that both procedures are equally effective in the treatment of menorrhagia. However, the ELITT procedure has proven to be superior in inducing amenorrhea.
Settore MED/40 - Ginecologia E Ostetricia
PERINO A, CASTELLI A, CUCINELLA G, BIONDO A, PANE A, & VENEZIA R (2004). A randomized comparison of endometrial laser intrauterine thermotherapy and hysteroscopic endometrial resection. FERTILITY AND STERILITY, 82(3), 731-734 [10.1016/j.fertnstert.2004.01.045].
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/34410
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