Background: Breast cancer is the most commonly diagnosed neoplasia in women after nonmelanoma skin tumors. Unfortunately, present-day diagnostic methods are unable to identify the presence of a cancer until it has been developing for several years. Currently, ductal lavage seems to represent a new method of reaching an early diagnosis of breast cancer. Materials & methods: This study analyzed 30 patients with ages ranging from 40 to 55 years; and in 26 of these patients, we were able to obtain a sufficient quantity of material for cytological and biomolecular analysis. Results & conclusion: We propose an easy, reproducible method that makes it possible to obtain a detailed map of the nipple, in order to re-identify the duct orifice and take a series of repeated samples from it over a period of time. This procedure is a promising screening and translational research tool since it provides the quantity and quality of ductal fluid required for subsequent cytological and biomolecular analyses
RUSSO A, GREGORIO V, SISTO P S, CAL V, AGNESE V, AUGELLO C, et al. (2006). Ductal lavage: a way of carefully tracing the breast-secreting duct. THERAPY, 3(3), 389-393 [10.2217/14750708.3.3.389].
Ductal lavage: a way of carefully tracing the breast-secreting duct
RUSSO, Antonio;GREGORIO, Valter;SISTO, Pasqua Sandra;AGNESE, Valentina;AUGELLO, Claudia;CASCIO, Sandra;BADALAMENTI, Giuseppe;NAPOLI, Luisa;GEBBIA, Nicolo';BAZAN, Viviana
2006-01-01
Abstract
Background: Breast cancer is the most commonly diagnosed neoplasia in women after nonmelanoma skin tumors. Unfortunately, present-day diagnostic methods are unable to identify the presence of a cancer until it has been developing for several years. Currently, ductal lavage seems to represent a new method of reaching an early diagnosis of breast cancer. Materials & methods: This study analyzed 30 patients with ages ranging from 40 to 55 years; and in 26 of these patients, we were able to obtain a sufficient quantity of material for cytological and biomolecular analysis. Results & conclusion: We propose an easy, reproducible method that makes it possible to obtain a detailed map of the nipple, in order to re-identify the duct orifice and take a series of repeated samples from it over a period of time. This procedure is a promising screening and translational research tool since it provides the quantity and quality of ductal fluid required for subsequent cytological and biomolecular analyses
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