Background. The natural history of atherosclerosis has not clearly been elucidated yet. Some works reported that flogosis plays a role in plaque instability. Why does this inflammatory process start? We investigated the correlation between Chlamydia pneumoniae acute infection and plaque rupture. Methods. We compared blood concentrations of IgM anti-Chlamydia pneumoniae in patients affected by acute myocardial infarction (AMI) and in patients affected by stable angina. Results. Our results showed a minimal statistical difference, with a more positive value in patients with AMI. Subsequently, the group affected by AMI was divided into two subgroups with and without plaque rupture: the subgroup with plaque rupture showed a higher blood concentration of Chlamydia antibodies. This subgroup was also divided into two other subgroups according to blood white cell concentration: the subgroup with normal concentration of white blood cells showed the highest value of Chlamydia antibodies. Conclusions. Chlamydia pneumoniae could play an important role in atherosclerotic plaque instability.
|Data di pubblicazione:||2006|
|Titolo:||LA CHLAMYDIA PNEUMONIAE È CORRELABILE CON LA ROTTURA DELLA PLACCA ATEROSCLEROTICA? RUPTURE OF THE ATHEROSCLEROTIC PLAQUE: IS CHLAMYDIA PNEUMONIAE A POSSIBLE AGENT?|
|Autori:||Fazio, G.; Sutera, L.; Zito, R.; Cascio, C.; Briguglia, D.; Taormina, S.; Giammanco, A.; Asennato, P.; Novo, S.|
|Tipologia:||Articolo su rivista|
|Citazione:||Fazio, G., Sutera, L., Zito, R., Cascio, C., Briguglia, D., Taormina, S., et al. (2006). LA CHLAMYDIA PNEUMONIAE È CORRELABILE CON LA ROTTURA DELLA PLACCA ATEROSCLEROTICA? RUPTURE OF THE ATHEROSCLEROTIC PLAQUE: IS CHLAMYDIA PNEUMONIAE A POSSIBLE AGENT?. GIORNALE ITALIANO DI CARDIOLOGIA, 7, 809-814.|
|Tipo:||Articolo in rivista|
|Appare nelle tipologie:||01 - Articolo su rivista|