Hepatocellular carcinoma (HCC) represents the fifth most common cancer and the third leading cause of cancer mortality worldwide, with a minority of patients surviving at 5 years from diagnosis, despite treatment. HCC usually develops in conditions of chronic liver disease (CLD), mostly on the background of a cirrhotic liver, with liver transplantation at present being the only treatment strategy to cure both HCC and the specific CLD.
Conigliaro, A., Tripodi, M., Parola, M. (2017). SENP1 activity sustains cancer stem cell in hypoxic HCC [10.1136/gutjnl-2017-313946].
SENP1 activity sustains cancer stem cell in hypoxic HCC
CONIGLIARO, Alice;
2017-01-01
Abstract
Hepatocellular carcinoma (HCC) represents the fifth most common cancer and the third leading cause of cancer mortality worldwide, with a minority of patients surviving at 5 years from diagnosis, despite treatment. HCC usually develops in conditions of chronic liver disease (CLD), mostly on the background of a cirrhotic liver, with liver transplantation at present being the only treatment strategy to cure both HCC and the specific CLD.
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