Left ventricular hypertrophy (LVH) develops in response to a variety of physical, genetic, and biochemical stimuli and represents the early stage of ventricular remodeling. In patients with LVH, subclinical left ventricular (LV) dysfunction despite normal ejection fraction (EF) may be present before the onset of symptoms, which portends a dismal prognosis. Strain measurement with two-dimensional speckle tracking echocardiography (STE) represents a highly reproducible and accurate alternative to LVEF determination. The present review focuses on current available evidence that supports the incremental value of STE in the diagnostic and prognostic workup of LVH. When assessing the components of LV contraction, STE has an incremental value in differentiating between primary and secondary LVH and in the differential diagnosis with storage diseases. In addition, STE provides unique information for the stratification of patients with LVH, enabling to detect intrinsic myocardial dysfunction before LVEF reduction.

D'Andrea, A., Radmilovic, J., Ballo, P., Mele, D., Agricola, E., Cameli, M., et al. (2017). Left ventricular hypertrophy or storage disease? the incremental value of speckle tracking strain bull's-eye. ECHOCARDIOGRAPHY, 34(5), 746-759 [10.1111/echo.13506].

Left ventricular hypertrophy or storage disease? the incremental value of speckle tracking strain bull's-eye

NOVO, Giuseppina;
2017-01-01

Abstract

Left ventricular hypertrophy (LVH) develops in response to a variety of physical, genetic, and biochemical stimuli and represents the early stage of ventricular remodeling. In patients with LVH, subclinical left ventricular (LV) dysfunction despite normal ejection fraction (EF) may be present before the onset of symptoms, which portends a dismal prognosis. Strain measurement with two-dimensional speckle tracking echocardiography (STE) represents a highly reproducible and accurate alternative to LVEF determination. The present review focuses on current available evidence that supports the incremental value of STE in the diagnostic and prognostic workup of LVH. When assessing the components of LV contraction, STE has an incremental value in differentiating between primary and secondary LVH and in the differential diagnosis with storage diseases. In addition, STE provides unique information for the stratification of patients with LVH, enabling to detect intrinsic myocardial dysfunction before LVEF reduction.
2017
D'Andrea, A., Radmilovic, J., Ballo, P., Mele, D., Agricola, E., Cameli, M., et al. (2017). Left ventricular hypertrophy or storage disease? the incremental value of speckle tracking strain bull's-eye. ECHOCARDIOGRAPHY, 34(5), 746-759 [10.1111/echo.13506].
File in questo prodotto:
File Dimensione Formato  
Left ventricular hypertrophy or storag....pdf

Solo gestori archvio

Dimensione 1.71 MB
Formato Adobe PDF
1.71 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/238323
Citazioni
  • ???jsp.display-item.citation.pmc??? 12
  • Scopus 37
  • ???jsp.display-item.citation.isi??? 32
social impact