Bronchial hyperreactivity seems to induce a loss of the deep inspiration's bronchoprotective effect which is normally able to dilate the obstructed airways. Studies such as the HRCT on the bronchial gauge's alterations show that the deep inspirations bronchodilator effect is associated with the bronchial distensibility. In fact, it is almost totally absent either in the elderly or in the COPD patients. In asthma, instead, the pathology's seriousness has proved to be associated with the impairment of the deep inspiration's broncho-protective effect which this way becomes an important diagnostic parameter.
SCICHILONE N, MARCHESE R, CATALANO F, BATTAGLIA S, GAGLIARDO C, & BELLIA V (2004). Iperreattività bronchiale e inspirazione profonda: correlazioni patogenetiche e implicazioni cliniche. GIORNALE ITALIANO DELLE MALATTIE DEL TORACE, 58(1), 62-67.