Forty-one children <8 years of age treated for brucellosis with oral minocycline (2.5 mg/kg) twice daily for 3 weeks were recalled and examined to check for dental staining and defects. Dental staining and defects were found in 14 of 41 exposed children (34.1%) and in 30 of 82 matched controls (36.6%), respectively (P > 0.2).
CASCIO A, DI LIBERTO C, D'ANGELO M, IARIA C, SCARLATA F, TITONE L, et al. (2004). No findings of dental defects in children treated with minocycline: a matched case-control study. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 48(7), 2739-2741.
No findings of dental defects in children treated with minocycline: a matched case-control study
CASCIO, ANTONIO;D'ANGELO, Matteo;SCARLATA, Francesco;CAMPISI, Giuseppina
2004-01-01
Abstract
Forty-one children <8 years of age treated for brucellosis with oral minocycline (2.5 mg/kg) twice daily for 3 weeks were recalled and examined to check for dental staining and defects. Dental staining and defects were found in 14 of 41 exposed children (34.1%) and in 30 of 82 matched controls (36.6%), respectively (P > 0.2).
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