Extracellular vesicles are recently described as specialized structures for intercellular communication. Their role in the central nervous system was diffusely studied in both physiological and pathological condition. In particular, an increased extracellular vesicle number was detected in several autoimmune diseases, including multiple sclerosis, a chronic autoimmune, inflammatory, demyelinating and neurodegenerative disease. This chapter summarizes the available information on the involvement of the extracellular vesicles in multiple sclerosis pathogenesis and their possible use as biomarker of therapy efficacy
Barreca, M.M., Aliotta, E., Geraci, F. (2017). Extracellular vesicles in multiple sclerosis as possible biomarkers: Dream or reality?. In Multiple Sclerosis: Bench to Bedside Global Perspectives on a Silent Killer (pp. 1-9). Springer [10.1007/978-3-319-47861-6_1].
Extracellular vesicles in multiple sclerosis as possible biomarkers: Dream or reality?
BARRECA, Maria Magdalena;GERACI, Fabiana
2017-01-01
Abstract
Extracellular vesicles are recently described as specialized structures for intercellular communication. Their role in the central nervous system was diffusely studied in both physiological and pathological condition. In particular, an increased extracellular vesicle number was detected in several autoimmune diseases, including multiple sclerosis, a chronic autoimmune, inflammatory, demyelinating and neurodegenerative disease. This chapter summarizes the available information on the involvement of the extracellular vesicles in multiple sclerosis pathogenesis and their possible use as biomarker of therapy efficacyFile | Dimensione | Formato | |
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