PURPOSE:To investigate if a congenital anomaly of the head of the optic nerve like such as tilted disc can be a risk factor for the development of optic disc drusen. METHODS:The study was performed retrospectively on the files of 47 patients with optic disc drusen. The diagnosis was confirmed by fluorescein angiography and B-scan ultrasonography. The authors examined the fundus photographs and the fluorescein angiographies of these patients looking for the presence of tilted discs. RESULTS:Two of the 47 patients with optic nerve drusen had tilted discs as well, about twice the expected rate. Both cases presented a parapapillary hemorrhage. CONCLUSIONS:The concomitant presence of tilted disc and optic disc drusen can have a cause-effect relationship. The axonal crowding in a scleral canal of reduced size, as seen in tilted disc, can compress the nerve fibers against the stiff lamina cribrosa, producing a chronic optic neuropathy leading to drusen.

GIUFFRE' G (2005). Optic disc drusen in tilted disc. EUROPEAN JOURNAL OF OPHTHALMOLOGY, 15(5), 647-651.

Optic disc drusen in tilted disc

GIUFFRE', Giuseppe
2005-01-01

Abstract

PURPOSE:To investigate if a congenital anomaly of the head of the optic nerve like such as tilted disc can be a risk factor for the development of optic disc drusen. METHODS:The study was performed retrospectively on the files of 47 patients with optic disc drusen. The diagnosis was confirmed by fluorescein angiography and B-scan ultrasonography. The authors examined the fundus photographs and the fluorescein angiographies of these patients looking for the presence of tilted discs. RESULTS:Two of the 47 patients with optic nerve drusen had tilted discs as well, about twice the expected rate. Both cases presented a parapapillary hemorrhage. CONCLUSIONS:The concomitant presence of tilted disc and optic disc drusen can have a cause-effect relationship. The axonal crowding in a scleral canal of reduced size, as seen in tilted disc, can compress the nerve fibers against the stiff lamina cribrosa, producing a chronic optic neuropathy leading to drusen.
2005
GIUFFRE' G (2005). Optic disc drusen in tilted disc. EUROPEAN JOURNAL OF OPHTHALMOLOGY, 15(5), 647-651.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/1934
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