This paper reviews the composition of colostrum and the potebntial preventive and therapeutic use of this "first milk" for treating various gastrointestinal disorders in humans. Colostrum is a complex biological liquid that is rich in antimicrobial peptides, immune-regulanting compounds and growth factors than the subsequent mature milk. The main functions of colostrum are to provide essential nutritional components, strenghten the natural defense system, modulate immune response, balance intestinal microbiota and enhance the growth and repair of several tissues. several studies and clinical trials carried out both in vitro and in vivo on humans and animals suggest the clinical benefits of bovine colostrum (BC) supplementation in gastro-intestinal diseases. Despite the encouraging results, there are no contraindications regarding high dose levels and few side effects of clinical relevance have been reported. In conclusion, in the near future, colostrum-based supplementations may be play a role to synthetic drugs in the prevention and treatment of various gastrointestinal disorders.

Menchetti, L., Traina, G., Tomasello, G., Casagrande-Proietti, P., Leonardi, L., Barbato, O., et al. (2016). POTENTIAL BENEFITS OF COLOSTRUM IN GASTROINTESTINAL DISEASES. FRONTIERS IN BIOSCIENCE, 8(1), 331-351 [10.2741/S467].

POTENTIAL BENEFITS OF COLOSTRUM IN GASTROINTESTINAL DISEASES

TOMASELLO, Giovanni;
2016-01-01

Abstract

This paper reviews the composition of colostrum and the potebntial preventive and therapeutic use of this "first milk" for treating various gastrointestinal disorders in humans. Colostrum is a complex biological liquid that is rich in antimicrobial peptides, immune-regulanting compounds and growth factors than the subsequent mature milk. The main functions of colostrum are to provide essential nutritional components, strenghten the natural defense system, modulate immune response, balance intestinal microbiota and enhance the growth and repair of several tissues. several studies and clinical trials carried out both in vitro and in vivo on humans and animals suggest the clinical benefits of bovine colostrum (BC) supplementation in gastro-intestinal diseases. Despite the encouraging results, there are no contraindications regarding high dose levels and few side effects of clinical relevance have been reported. In conclusion, in the near future, colostrum-based supplementations may be play a role to synthetic drugs in the prevention and treatment of various gastrointestinal disorders.
2016
Menchetti, L., Traina, G., Tomasello, G., Casagrande-Proietti, P., Leonardi, L., Barbato, O., et al. (2016). POTENTIAL BENEFITS OF COLOSTRUM IN GASTROINTESTINAL DISEASES. FRONTIERS IN BIOSCIENCE, 8(1), 331-351 [10.2741/S467].
File in questo prodotto:
File Dimensione Formato  
Potential benefits of colostrum in gastrointestinal diseases-Frontiers in Bioscience scholar 2016.pdf

Solo gestori archvio

Dimensione 403.61 kB
Formato Adobe PDF
403.61 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/178692
Citazioni
  • ???jsp.display-item.citation.pmc??? 28
  • Scopus 56
  • ???jsp.display-item.citation.isi??? ND
social impact