We herein describe two severe cases of Mediterranean spotted fever caused by Rickettsia conorii. The ar- ticle presents polymerase chain reaction-restriction analysis as an early diagnostic tool for rickettsiosis caused by spotted fever group Rickettsiae. Timely microbiological diagnosis, the combined use of antibi- otics, intensive care measures and a multidisciplinary team approach are fundamental to manage these serious diseases.
Di Carlo, P., Trizzino, M., Giarratano, A., Giammanco, A., Montalto, F., Raineri, M., et al. (2015). Real-time PCR for early diagnosis of Rickettsia conorii and prompt management in patients with septic shock and multiple organ failure: two case reports. INFECTIOUS DISEASES AND TROPICAL MEDICINE.
Real-time PCR for early diagnosis of Rickettsia conorii and prompt management in patients with septic shock and multiple organ failure: two case reports
DI CARLO, Paola;TRIZZINO, Marcello;GIARRATANO, Antonino;GIAMMANCO, Anna;MONTALTO, Francesca;RAINERI, Santi Maurizio;BONURA, Celestino
2015-01-01
Abstract
We herein describe two severe cases of Mediterranean spotted fever caused by Rickettsia conorii. The ar- ticle presents polymerase chain reaction-restriction analysis as an early diagnostic tool for rickettsiosis caused by spotted fever group Rickettsiae. Timely microbiological diagnosis, the combined use of antibi- otics, intensive care measures and a multidisciplinary team approach are fundamental to manage these serious diseases.
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