Pharmacokinetic (PK) studies on recombinant FIX concentrate, Nonacog alpha, were conducted with different sampling time designs which gave rise to not complete and homogenous outcomes. In addition, patient's FIX genotype/PK relationship has never been investigated.
Morfini, M., Dragani, A., Paladino, E., Radossi, P., Di Minno, G., Mazzucconi, M., et al. (2016). Correlation between FIX genotype and pharmacokinetics of Nonacog alpha according to a multicentre Italian study. HAEMOPHILIA, n/a-n/a [10.1111/hae.12916].
Correlation between FIX genotype and pharmacokinetics of Nonacog alpha according to a multicentre Italian study
NAPOLITANO, Mariasanta;
2016-01-01
Abstract
Pharmacokinetic (PK) studies on recombinant FIX concentrate, Nonacog alpha, were conducted with different sampling time designs which gave rise to not complete and homogenous outcomes. In addition, patient's FIX genotype/PK relationship has never been investigated.
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