Guillain-Barré Syndrome (GBS) is a demyelinating polyneuropathy of probable autoimmune pathogenesis characterized by rapidly progressive symmetric paralysis. In the literature some cases of GBS associated with anticancer chemotherapy are reported. We present a case of a 55-year old woman who complained of progressive motor deficit in four limbs, areflexia in lower limbs and facial nerve paralysis one week after beginning cisplatin-gemcitabine chemotherapy for metastatic lung cancer. The cerebrospinal fluid analysis showed a strong positive Pandy reaction with 435 mg/dl total protein. The electromyography and the electroneuronography established the diagnosis of inflammatory demyelinating polyneuropathy. Specific therapy with intravenous immunoglobulin 25 g/day in 5 administrations for 5 days was started with complete benefit.
|Data di pubblicazione:||2006|
|Titolo:||A case of guillain-barre syndrome in a patient with non small cell lung cancer treated with chemotherapy|
|Autori:||CICERO G; FULFARO F; CARACENI A; ARCARA C; BADALAMENTI G; INTRIVICI C; GEBBIA N|
|Tipologia:||Articolo su rivista|
|Citazione:||CICERO G, FULFARO F, CARACENI A, ARCARA C, BADALAMENTI G, INTRIVICI C, et al. (2006). A case of guillain-barre syndrome in a patient with non small cell lung cancer treated with chemotherapy. JOURNAL OF CHEMOTHERAPY, 18, 325-327.|
|Appare nelle tipologie:||01 - Articolo su rivista|