The aim of the present study was to evaluate the effect of a single haemodialysis (HD) session on serum fetuin-A levels, considered a negative acute phase response marker; moreover, we evaluated the behaviour of fibrinogen and high sensitivity C-reactive protein (hsCRP) as acute phase response and chronic/subclinical inflammation markers, respectively, after a single HD session. Serum fetuin-A, albumin, hsCRP and fibrinogen were measured in 72 patients before and after a single HD session. After a single HD session, we observed a significant increase in fibrinogen levels, while fetuin-A levels decreased (p<0.05). Also, hsCRP levels were significantly increased. The significant decrease of fetuin-A levels after a single HD session is consistent with the hypothesis of HD-induced inflammation; activated acute phase response and fetuin-A deficiency might account for increased cardiovascular risk and accelerated atherogenesis in dialysis patients.
|Data di pubblicazione:||2008|
|Titolo:||Changes in serum Fetuin A and inflammatory markers levels in end stage renal disease (ESRD),effect of a single session haemodialysis|
|Autori:||CIACCIO, M; BIVONA, G; DI SCIACCA, R; IATRINO, R; DI NATALE, E; LI VECCHI, M; BELLIA, C|
|Tipologia:||Articolo su rivista|
|Citazione:||CIACCIO, M., BIVONA, G., DI SCIACCA, R., IATRINO, R., DI NATALE, E., LI VECCHI, M., et al. (2008). Changes in serum Fetuin A and inflammatory markers levels in end stage renal disease (ESRD),effect of a single session haemodialysis. CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2008, 212-214.|
|Appare nelle tipologie:||01 - Articolo su rivista|