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EnglishBackground: Few studies exist on ERPs and patients with subcortical vascular cognitive impairment (SVCI). This latter is a quite homogeneous subtype of vascular dementia whose cognitive profile is quite different from that of Alzheimer disease (AD). The present study aims at comparing the ERPs profile both in patients with SVCI and in patients with AD. Our finding suggest that these two dementing diseases have different electrophysiologic features that may be related to their specific underlying pathogenetic mechanism; in particular, we hypothesise that, differently from AD, P300 latency prolongation characterizes the early stage of SVCI. So, this ERPs approach could be helpful to detect early alterations of the attentional/working-memory functions in patients with subcortical ischaemic vascular disease.
Muscoso, E., Costanzo, E., Daniele, O., Maugeri, D., Natale, E., & Caravaglios, G. (2006). Auditory event-related potentials in subcortical vascular cognitive impairment and in Alzheimer's disease. JOURNAL OF NEURAL TRANSMISSION, 113(11), 1779-1786.
| Data di pubblicazione: | 2006 |
| Titolo: | Auditory event-related potentials in subcortical vascular cognitive impairment and in Alzheimer's disease. |
| Autori: | |
| Citazione: | Muscoso, E., Costanzo, E., Daniele, O., Maugeri, D., Natale, E., & Caravaglios, G. (2006). Auditory event-related potentials in subcortical vascular cognitive impairment and in Alzheimer's disease. JOURNAL OF NEURAL TRANSMISSION, 113(11), 1779-1786. |
| Rivista: | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1007/s00702-006-0574-7 |
| Abstract: | Background: Few studies exist on ERPs and patients with subcortical vascular cognitive impairment (SVCI). This latter is a quite homogeneous subtype of vascular dementia whose cognitive profile is quite different from that of Alzheimer disease (AD). The present study aims at comparing the ERPs profile both in patients with SVCI and in patients with AD. Our finding suggest that these two dementing diseases have different electrophysiologic features that may be related to their specific underlying pathogenetic mechanism; in particular, we hypothesise that, differently from AD, P300 latency prolongation characterizes the early stage of SVCI. So, this ERPs approach could be helpful to detect early alterations of the attentional/working-memory functions in patients with subcortical ischaemic vascular disease. |
| Settore Scientifico Disciplinare: | Settore MED/26 - Neurologia |
| Appare nelle tipologie: | 1.01 Articolo in rivista |
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